ACVR2A Products
(Activin A Receptor, Type IIA (ACVR2A))
Categories
This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. [provided by RefSeq, Jul 2008].
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Featured ACVR2A Categories
ACVR2A Antibodies
High quality antibodies with extensive validation data.
ACVR2A ELISA Kits
Reliable ELISA kits for a wide range of species.
ACVR2A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACVR2A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (9)
Cat. No.
ABIN7438676
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
Cat. No.
ABIN3015792
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7427552
Quantity
100 μL
Datasheet
Datasheet
Recommended ACVR2A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6953429
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964578
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4881727
Quantity
96 tests
Datasheet
Datasheet
Recommended ACVR2A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305813
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305811
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN5854601
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ACVR2A products
: "ActivinA: a new leukemia-promoting factor conferring migratory advantage to B-cell precursor-acute lymphoblastic leukemic cells." in: Haematologica, Vol. 104, Issue 3, pp. 533-545, (2019) (PubMed).: "A follistatin-based molecule increases muscle and bone mass without affecting the red blood cell count in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 5, pp. 6001-6010, (2019) (PubMed).
: "Detection of Sotatercept (ACE-011) in human serum by SAR-PAGE and western single blotting." in: Drug testing and analysis, Vol. 10, Issue 6, pp. 927-937, (2018) (PubMed).
: "Modulation of noncanonical TGF-? signaling prevents cleft palate in Tgfbr2 mutant mice." in: The Journal of clinical investigation, Vol. 122, Issue 3, pp. 873-85, (2012) (PubMed).
: "Expression of activin subunits and receptors in the developing human ovary: activin A promotes germ cell survival and proliferation before primordial follicle formation." in: Developmental biology, Vol. 266, Issue 2, pp. 334-45, (2004) (PubMed).
: "Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers." in: Gastroenterology, Vol. 126, Issue 3, pp. 654-9, (2004) (PubMed).
: "Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 83, Issue 12, pp. 1867-71, (2003) (PubMed).
Synonyms and alternative names related to ACVR2A
activin A receptor type 2A (ACVR2A), activin A receptor type 2A (acvr2a), activin A receptor type 2A (Acvr2a), activin A receptor type 2A L homeolog (acvr2a.L), activin A receptor type 2Aa (acvr2aa), activin receptor IIA (Acvr2a), actr2a, actrii, ACTRII, ActrIIa, ACVR2, acvr2, Acvr2, ACVR2A, acvr2a, rActR-II, TactrII, wu:fa02e10, XSTK9Protein level used designations for ACVR2A
- activin receptor IIA
- activin receptor type-2A
- activin A receptor, type IIA
- ACTR-IIA
- activin receptor type IIA
- type II activin receptor
- activin A receptor, type II
- activin receptor, type IIA
- ACTRIIA
- activin receptor type II
- activin type 2 receptor
- activin receptor IIa
- etID22865.9
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