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ACVR1C/ALK7 Products

(Activin Receptor Type 1C (ACVR1C))

Categories

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008].

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Featured ACVR1C/ALK7 Categories

ACVR1C/ALK7 Antibodies

High quality antibodies with extensive validation data.

ACVR1C/ALK7 ELISA Kits

Reliable ELISA kits for a wide range of species.

ACVR1C/ALK7 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ACVR1C/ALK7 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7143179
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN714596
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN391157
Quantity 400 μL
Datasheet Datasheet

Recommended ACVR1C/ALK7 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN2747946
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6226424
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385787
Quantity 96 tests
Datasheet Datasheet

Recommended ACVR1C/ALK7 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN4369914
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7491395
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305809
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ACVR1C/ALK7 products

Tengroth, Arebro, Larsson, Bachert, Georén, Cardell: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." in: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).

Puvanenthiran, Essapen, Seddon, Modjtahedi et al.: "Impact of the putative cancer stem cell markers and growth factor receptor expression on the sensitivity of ovarian cancer cells to treatment with various forms of small molecule tyrosine kinase ..." in: International journal of oncology, Vol. 49, Issue 5, pp. 1825-1838, (2017) (PubMed).

Liu, Yang, Li, Liu, Miao, Yang, Zou, Yuan: "Overexpression of B2M and loss of ALK7 expression are associated with invasion, metastasis, and poor-prognosis of the pancreatic ductal adenocarcinoma." in: Cancer biomarkers : section A of Disease markers, Vol. 15, Issue 6, pp. 735-43, (2015) (PubMed).

Huang, Tang, Wu, Mei, Liu, Liu, Wan, Liu, Huang: "ALK7 protects against pathological cardiac hypertrophy in mice." in: Cardiovascular research, Vol. 108, Issue 1, pp. 50-61, (2015) (PubMed).

Kim, van Gelder, Kim, Lee, Baik, Chun, Lee, Choi, Kim: "Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells." in: The Journal of biological chemistry, Vol. 279, Issue 27, pp. 28458-65, (2004) (PubMed).

Munir, Xu, Wu, Yang, Lala, Peng: "Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31277-86, (2004) (PubMed).

Roberts, Hu, Qiu, Leung, Caniggia, Gruslin, Tsang, Peng: "Identification of novel isoforms of activin receptor-like kinase 7 (ALK7) generated by alternative splicing and expression of ALK7 and its ligand, Nodal, in human placenta." in: Biology of reproduction, Vol. 68, Issue 5, pp. 1719-26, (2003) (PubMed).

Synonyms and alternative names related to ACVR1C/ALK7

activin A receptor type 1C (ACVR1C), activin A receptor, type IC (Acvr1c), activin A receptor type 1C (Acvr1c), ACVRLK7, Alk-7, ALK7, Alk7, C230097P10, habrec1

Protein level used designations for ACVR1C/ALK7

  • ACTR-IC
  • ALK-7
  • activin receptor type IC
  • activin receptor type-1C
  • activin receptor-like kinase 7
  • TGF-beta type 1 receptor
  • activin A receptor, type IC
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