ACTN2 Products
(Actinin, alpha 2 (ACTN2))
Categories
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. [provided by RefSeq, Jul 2008].
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Featured ACTN2 Categories
ACTN2 Antibodies
High quality antibodies with extensive validation data.
ACTN2 ELISA Kits
Reliable ELISA kits for a wide range of species.
ACTN2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACTN2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IF, IHC (p)
Validations
- (1)
- (7)
Cat. No.
ABIN2855582
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, StM
Validations
- (6)
Cat. No.
ABIN6940980
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, StM
Validations
- (6)
Cat. No.
ABIN6940979
Quantity
100 μg
Datasheet
Datasheet
Recommended ACTN2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964557
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953409
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Pig
Analytical Method
Quantitative Competition ELISA
Validations
Cat. No.
ABIN777955
Quantity
96 tests
Datasheet
Datasheet
Recommended ACTN2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390205
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7390208
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3088293
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ACTN2 products
: "Acute AT1R blockade prevents isoproterenol-induced injury in mdx hearts." in: Journal of molecular and cellular cardiology, Vol. 128, pp. 51-61, (2019) (PubMed).: "Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions." in: Developmental cell, Vol. 44, Issue 1, pp. 87-96.e5, (2018) (PubMed).
: "Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training." in: PeerJ, Vol. 6, pp. e5338, (2018) (PubMed).
: "Composite poly(lactic acid)/chitosan nanofibrous scaffolds for cardiac tissue engineering." in: International journal of biological macromolecules, Vol. 103, pp. 1130-1137, (2017) (PubMed).
: "T3 inhibits the calcification of vascular smooth muscle cells and the potential mechanism." in: American journal of translational research, Vol. 8, Issue 11, pp. 4694-4704, (2016) (PubMed).
: "Effects of BMSCs interactions with adventitial fibroblasts in transdifferentiation and ultrastructure processes." in: International journal of clinical and experimental pathology, Vol. 7, Issue 7, pp. 3957-65, (2015) (PubMed).
: "Expression patterns of sarcomeric ?-actin, ?-actinin and UCP2 in the myocardium of Kunming mice after exposure to c-terminal polypeptide of cardiotrophin-1." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 6, pp. 796-800, (2014) (PubMed).
: "Similar to spironolactone, oxymatrine is protective in aldosterone-induced cardiomyocyte injury via inhibition of calpain and apoptosis-inducing factor signaling." in: PLoS ONE, Vol. 9, Issue 2, pp. e88856, (2014) (PubMed).
: "Activation of an apoptotic signal transduction pathway involved in the upregulation of calpain and apoptosis-inducing factor in aldosterone-induced primary cultured cardiomyocytes." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 53, pp. 364-70, (2013) (PubMed).
: "Inhaled corticosteroids inhibit substance P receptor expression in asthmatic rat airway smooth muscle cells." in: BMC pulmonary medicine, Vol. 12, pp. 79, (2013) (PubMed).
Synonyms and alternative names related to ACTN2
actinin alpha 2 (actn2), actinin alpha 2 (ACTN2), actinin alpha 2 (Actn2), actinin, alpha 2b (actn2b), actinin alpha 2 S homeolog (actn2.S), 1110008F24Rik, ACTN2, CMD1AA, MGC89234, wu:fd44c03, zgc:123223Protein level used designations for ACTN2
- actinin, alpha 2
- alpha 2 actinin
- alpha-actinin-2-like
- F-actin cross-linking protein
- alpha-actinin skeletal muscle
- alpha-actinin-2
Did you look for something else?
- ACTN1/2/3/4
- ACTN1
- ACTL9
- Actl7b
- ACTL10
- Activin-beta
- Activin Receptor Type II
- Activin B
- Activin AB
- Activin A Receptor Type IB/ALK-4
- Activator of Basal Transcription 1
- Activating Transcription Factor 7
- Activated Protein C
- Activated Leukocyte Cell Adhesion Molecule
- Actin, Muscle Specific
- Actin, gamma 1
- Actin, Beta, gamma
- Actin, beta 2
- Actin, Alpha, gamma
- Actin, Alpha, Cardiac Muscle 1
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