ACTN1 Products
(Actinin, alpha 1 (ACTN1))
Categories
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured ACTN1 Categories
ACTN1 Antibodies
High quality antibodies with extensive validation data.
ACTN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ACTN1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACTN1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (3)
- (6)
Cat. No.
ABIN3021587
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey, Mouse
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7255688
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN652451
Quantity
400 μL
Datasheet
Datasheet
Recommended ACTN1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953408
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5591617
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN579565
Quantity
96 tests
Datasheet
Datasheet
Recommended ACTN1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121663
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305770
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305768
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our ACTN1 products
: "Upregulation of heat shock protein 70 and the differential protein expression induced by tumor necrosis factor-alpha enhances migration and inhibits apoptosis of hepatocellular carcinoma cell HepG2." in: International journal of medical sciences, Vol. 14, Issue 3, pp. 284-293, (2017) (PubMed).: "Protein kinase A inhibitor, H89, significantly enhances survival rate of dissociated human embryonic stem cells following cryopreservation." in: Cell proliferation, Vol. 49, Issue 5, pp. 589-98, (2017) (PubMed).
: "Functional Human Podocytes Generated in Organoids from Amniotic Fluid Stem Cells." in: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 5, pp. 1400-11, (2017) (PubMed).
: "The Power of Human Protective Modifiers: PLS3 and CORO1C Unravel Impaired Endocytosis in Spinal Muscular Atrophy and Rescue SMA Phenotype. ..." in: American journal of human genetics, Vol. 99, Issue 3, pp. 647-65, (2016) (PubMed).
: "miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 34, pp. 9551-6, (2016) (PubMed).
: "Protein kinase A inhibitor, H89, enhances survival and clonogenicity of dissociated human embryonic stem cells through Rho-associated coiled-coil containing protein kinase (ROCK) inhibition." in: Human reproduction (Oxford, England), Vol. 31, Issue 4, pp. 832-43, (2016) (PubMed).
: "Sensitivity of human embryonic stem cells to different conditions during cryopreservation." in: Cryobiology, Vol. 71, Issue 3, pp. 486-92, (2016) (PubMed).
: "Urinary candidate biomarker discovery in a rat unilateral ureteral obstruction model." in: Scientific reports, Vol. 5, pp. 9314, (2015) (PubMed).
: "Involvement of ubiquitin-conjugating enzyme E2C in proliferation and invasion of prostate carcinoma cells." in: Oncology research, Vol. 21, Issue 3, pp. 121-7, (2014) (PubMed).
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).
Synonyms and alternative names related to ACTN1
actinin alpha 1 (ACTN1), actinin alpha 1 (actn1), actinin, alpha 1 (ACTN1), actinin, alpha 1 (Actn1), actinin, alpha 1 (actn1), actinin alpha 1 L homeolog (actn1.L), 3110023F10Rik, actinin, ACTN1, Actn1a, BDPLT15Protein level used designations for ACTN1
- actinin, alpha 1
- alpha actinin
- Alpha-actinin-1
- alpha-actinin-1
- F-actin cross-linking protein
- actinin 1 smooth muscle
- alpha-actinin cytoskeletal isoform
- non-muscle alpha-actinin-1
- alpha actinin 1a
- non-muscle alpha-actinin 1
- alpha-actinin 1
Did you look for something else?
- ACTL9
- Actl7b
- ACTL10
- Activin-beta
- Activin Receptor Type II
- Activin B
- Activin AB
- Activin A Receptor Type IB/ALK-4
- Activator of Basal Transcription 1
- Activating Transcription Factor 7
- Activated Protein C
- Activated Leukocyte Cell Adhesion Molecule
- Actin, Muscle Specific
- Actin, gamma 1
- Actin, Beta, gamma
- Actin, beta 2
- Actin, Alpha, gamma
- Actin, Alpha, Cardiac Muscle 1
- Actin, alpha 2, Smooth Muscle, Aorta
- Actin, alpha 1, Skeletal Muscle
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