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Actl7b Products

(Actin-Like 7b (Actl7b))

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The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene (ACTL7B), and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known. [provided by RefSeq, Jul 2008].

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Featured Actl7b Categories

Actl7b Antibodies

High quality antibodies with extensive validation data.

Actl7b Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Actl7b Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
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Cat. No. ABIN7143059
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IP
Validations
  • (2)
Cat. No. ABIN524278
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN564727
Quantity 100 μg
Datasheet Datasheet

Recommended Actl7b ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6212510
Quantity 96 tests
Datasheet Datasheet

Recommended Actl7b Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305762
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305764
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088122
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Actl7b products

Cadalbert, Ghaffar, Stevenson, Bryson, Vaz, Gottlieb, Strathdee: "Mouse Tafazzin Is Required for Male Germ Cell Meiosis and Spermatogenesis." in: PLoS ONE, Vol. 10, Issue 6, pp. e0131066, (2015) (PubMed).

Djureinovic, Fagerberg, Hallström, Danielsson, Lindskog, Uhlén, Pontén: "The human testis-specific proteome defined by transcriptomics and antibody-based profiling." in: Molecular human reproduction, Vol. 20, Issue 6, pp. 476-88, (2014) (PubMed).

Andersson, Konrad, Ashok, Pontén, Hober, Asplund: "Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 11, pp. 773-84, (2013) (PubMed).

Chadwick, Mull, Helbling, Gill, Leyne, Robbins, Pinkett, Makalowska, Maayan, Blumenfeld, Axelrod, Brownstein, Gusella, Slaugenhaupt: "Cloning, mapping, and expression of two novel actin genes, actin-like-7A (ACTL7A) and actin-like-7B (ACTL7B), from the familial dysautonomia candidate region on 9q31." in: Genomics, Vol. 58, Issue 3, pp. 302-9, (1999) (PubMed).

Synonyms and alternative names related to Actl7b

actin-like 7b (Actl7b), actin like 7B (ACTL7B), ACTL7B, Tact1

Protein level used designations for Actl7b

  • actin-like protein 7B
  • actin-like 7B
  • actin-like 7-beta
  • actin-like-7-beta
  • T-actin-1
  • t-actin 1
  • testis-specific actin-1
  • actin-like protein 7B-like
  • Actin-like-7-beta
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