Actin-Like 6A Products
(Actin-Like 6A (BAF53A))
Categories
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila\; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008].
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Featured Actin-Like 6A Categories
Actin-Like 6A Antibodies
High quality antibodies with extensive validation data.
Actin-Like 6A ELISA Kits
Reliable ELISA kits for a wide range of species.
Actin-Like 6A Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Actin-Like 6A Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, ChIP
Validations
- (3)
Cat. No.
ABIN7143052
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, IHC (p)
Validations
- (3)
Cat. No.
ABIN6243024
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN513096
Quantity
100 μg
Datasheet
Datasheet
Recommended Actin-Like 6A ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953404
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648156
Quantity
96 tests
Datasheet
Datasheet
Recommended Actin-Like 6A Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305755
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305757
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305753
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Actin-Like 6A products
: "A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells." in: Nature communications, Vol. 9, Issue 1, pp. 5139, (2019) (PubMed).: "TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin." in: Nature structural & molecular biology, Vol. 24, Issue 4, pp. 344-352, (2017) (PubMed).
: "ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4." in: Cell stem cell, Vol. 12, Issue 2, pp. 193-203, (2013) (PubMed).
: "Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 25, pp. 10348-61, (2013) (PubMed).
: "Two isoforms of a human actin-related protein show nuclear localization and mutually selective expression between brain and other tissues." in: Bioscience, biotechnology, and biochemistry, Vol. 63, Issue 5, pp. 917-23, (1999) (PubMed).
: "Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers." in: eLife, Vol. 6 (PubMed).
Synonyms and alternative names related to Actin-Like 6A
actin like 6A (ACTL6A), actin-like 6A (Actl6a), actin-like 6A (actl6a), actin like 6A (actl6a), actin-related protein 4 (ARP4), actin like 6A (Actl6a), Arp4p (ARP4), actin like 6A S homeolog (actl6a.S), 2810432C06Rik, actin, Actin-like protein 4, actin-related protein 4, ACTL6, Actl6, actl6, ACTL6A, actl6a, actl6a.L, AI851094, Arp4, ARP4, arp4, ARPN-BETA, arpn-beta, ATARP4, BAF53A, Baf53a, baf53a, C79802, CaO19.5623, chunp6900, F15H18.8, F15H18_8, fb52e06, fl26e12, INO80K, ino80k, MGC75671, RGD1307747, wu:fb52e06, wu:fl26e12Protein level used designations for Actin-Like 6A
- 53 kDa BRG1-associated factor A
- BAF complex 53 kDa subunit
- BAF53
- BRG1-associated factor 53A
- INO80 complex subunit K
- actin-like protein 6A
- actin-related protein 4
- actin-related protein Baf53a
- arpNbeta
- hArpN beta
- BRG1/brm-associated factor 53A
- actin-like 6
- actin-like 6A
- etID38198.6
- actin-like protein 6A-like
- Actin-like protein ARP4
- actin like 6A L homeolog
- actin like 6A S homeolog
- actin-related protein
Did you look for something else?
- Actin Related Protein 2/3 Complex, Subunit 5, 16kDa
- Actin Related Protein 2/3 Complex, Subunit 5-Like
- Actin Filament Associated Protein 1-Like 1
- Actin Binding LIM Protein 1
- Actin
- ACTH
- ACTG2
- ACTBL3
- ACTBL2
- ACTA1/ACTA2A/ACTG2
- ACSS3
- ACSS2
- ACSS1
- ACSM5
- ACSM4
- ACSM3
- ACSM2A
- ACSM2
- ACSM1
- ACSL6
- Actin-Like 6B
- Actin-Like 7A
- Actin-Like 8
- Actin-Related Protein 2
- Actin, alpha 1, Skeletal Muscle
- Actin, alpha 2, Smooth Muscle, Aorta
- Actin, Alpha, Cardiac Muscle 1
- Actin, Alpha, gamma
- Actin, beta 2
- Actin, Beta, gamma
- Actin, gamma 1
- Actin, Muscle Specific
- Activated Leukocyte Cell Adhesion Molecule
- Activated Protein C
- Activating Transcription Factor 7
- Activator of Basal Transcription 1
- Activin A Receptor Type IB/ALK-4
- Activin AB
- Activin B
- Activin Receptor Type II
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