Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Actin-Like 6A Products

(Actin-Like 6A (BAF53A))

Categories

This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila\; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described. [provided by RefSeq, Jul 2008].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured Actin-Like 6A Categories

Actin-Like 6A Antibodies

High quality antibodies with extensive validation data.

Actin-Like 6A ELISA Kits

Reliable ELISA kits for a wide range of species.

Actin-Like 6A Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Actin-Like 6A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, ChIP
Validations
  • (3)
Cat. No. ABIN7143052
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
Cat. No. ABIN6243024
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN513096
Quantity 100 μg
Datasheet Datasheet

Recommended Actin-Like 6A ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953404
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN5648156
Quantity 96 tests
Datasheet Datasheet

Recommended Actin-Like 6A Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305755
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305757
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305753
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Actin-Like 6A products

Gatchalian, Malik, Ho, Lee, Kelso, Shokhirev, Dixon, Hargreaves: "A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells." in: Nature communications, Vol. 9, Issue 1, pp. 5139, (2019) (PubMed).

Miller, Hargreaves, Kadoch, Chang, Calarco, Hodges, Buenrostro, Cui, Greenleaf, Zhao, Crabtree: "TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin." in: Nature structural & molecular biology, Vol. 24, Issue 4, pp. 344-352, (2017) (PubMed).

Bao, Tang, Lopez-Pajares, Tao, Qu, Crabtree, Khavari: "ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4." in: Cell stem cell, Vol. 12, Issue 2, pp. 193-203, (2013) (PubMed).

Staahl, Tang, Wu, Sun, Gitler, Yoo, Crabtree: "Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 25, pp. 10348-61, (2013) (PubMed).

Harata, Mochizuki, Mizuno: "Two isoforms of a human actin-related protein show nuclear localization and mutually selective expression between brain and other tissues." in: Bioscience, biotechnology, and biochemistry, Vol. 63, Issue 5, pp. 917-23, (1999) (PubMed).

Kelso, Porter, Amaral, Shokhirev, Benner, Hargreaves: "Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers." in: eLife, Vol. 6 (PubMed).

Synonyms and alternative names related to Actin-Like 6A

actin like 6A (ACTL6A), actin-like 6A (Actl6a), actin-like 6A (actl6a), actin like 6A (actl6a), actin-related protein 4 (ARP4), actin like 6A (Actl6a), Arp4p (ARP4), actin like 6A S homeolog (actl6a.S), 2810432C06Rik, actin, Actin-like protein 4, actin-related protein 4, ACTL6, Actl6, actl6, ACTL6A, actl6a, actl6a.L, AI851094, Arp4, ARP4, arp4, ARPN-BETA, arpn-beta, ATARP4, BAF53A, Baf53a, baf53a, C79802, CaO19.5623, chunp6900, F15H18.8, F15H18_8, fb52e06, fl26e12, INO80K, ino80k, MGC75671, RGD1307747, wu:fb52e06, wu:fl26e12

Protein level used designations for Actin-Like 6A

  • 53 kDa BRG1-associated factor A
  • BAF complex 53 kDa subunit
  • BAF53
  • BRG1-associated factor 53A
  • INO80 complex subunit K
  • actin-like protein 6A
  • actin-related protein 4
  • actin-related protein Baf53a
  • arpNbeta
  • hArpN beta
  • BRG1/brm-associated factor 53A
  • actin-like 6
  • actin-like 6A
  • etID38198.6
  • actin-like protein 6A-like
  • Actin-like protein ARP4
  • actin like 6A L homeolog
  • actin like 6A S homeolog
  • actin-related protein
You are here:
Support