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ACTH Proteins

(Adrenocorticotropic hormone (ACTH))
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the polypeptide precursor and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used\; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].
ACTH Protein (AA 27-235) (His tag) (ABIN7505394)

ACTH Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

ACTH Protein (ABIN2746199)

ACTH Origin: Mouse, Human, Rat Host: Escherichia coli (E. coli) Recombinant PC, WB

ACTH Protein (ABIN1061222)

ACTH Origin: Hormone greater than 98 %

ACTH Proteins by Origin

Find ACTH Proteins for a variety of species such as anti-Mouse ACTH, anti-Hormone ACTH, anti-Human ACTH. The species listed below are among those available. Click on a link to go to the corresponding products.

ACTH Proteins by Source

Here you will find ACTH Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ACTH Proteins by Protein Type

Here you can find ACTH Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

ACTH Proteins by Application

Find ACTH Proteins validated for a specific application such as PC, WB. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ACTH Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7505394
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2746199
Quantity 5 applications
Datasheet Datasheet
Reactivity Hormone
Source
Validations
Cat. No. ABIN1061222
Quantity 10 mg
Datasheet Datasheet

Aliases for ACTH Proteins

pro-opiomelanocortin-alpha (Pomc) Proteins
proopiomelanocortin (POMC) Proteins
ACTH Proteins
alpha-MSH Proteins
alphaMSH Proteins
BE Proteins
Beta-LPH Proteins
beta-MSH Proteins
Clip Proteins
CLIP Proteins
Gamma-LPH Proteins
gamma-MSH Proteins
LPH Proteins
MSH Proteins
Npp Proteins
NPP Proteins
POC Proteins
Pomc-1 Proteins
Pomc1 Proteins
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