ACSL5 Products
(Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5))
Categories
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured ACSL5 Categories
ACSL5 Antibodies
High quality antibodies with extensive validation data.
ACSL5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACSL5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (4)
- (6)
Cat. No.
ABIN565656
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7158511
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN1678546
Quantity
100 μg
Datasheet
Datasheet
Recommended ACSL5 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6212508
Quantity
96 tests
Datasheet
Datasheet
Recommended ACSL5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305721
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305719
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3119063
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ACSL5 products
: "Lactobacillus gasseri in the Upper Small Intestine Impacts an ACSL3-Dependent Fatty Acid-Sensing Pathway Regulating Whole-Body Glucose Homeostasis." in: Cell metabolism, Vol. 27, Issue 3, pp. 572-587.e6, (2018) (PubMed).: "Lipid droplet remodeling and interaction with mitochondria in mouse brown adipose tissue during cold treatment." in: Biochimica et biophysica acta, Vol. 1853, Issue 5, pp. 918-28, (2015) (PubMed).
: "TP53 status regulates ACSL5-induced expression of mitochondrial mortalin in enterocytes and colorectal adenocarcinomas." in: Cell and tissue research, Vol. 357, Issue 1, pp. 267-78, (2014) (PubMed).
: "Modulating effects of acyl-CoA synthetase 5-derived mitochondrial Wnt2B palmitoylation on intestinal Wnt activity." in: World journal of gastroenterology : WJG, Vol. 20, Issue 40, pp. 14855-64, (2014) (PubMed).
: "Diminished acyl-CoA synthetase isoform 4 activity in INS 832/13 cells reduces cellular epoxyeicosatrienoic acid levels and results in impaired glucose-stimulated insulin secretion." in: The Journal of biological chemistry, Vol. 288, Issue 30, pp. 21618-29, (2013) (PubMed).
: "Promotion of glioma cell survival by acyl-CoA synthetase 5 under extracellular acidosis conditions." in: Oncogene, Vol. 28, Issue 1, pp. 9-19, (2009) (PubMed).
: "Gene expression profiling in sinonasal adenocarcinoma." in: BMC medical genomics, Vol. 2, pp. 65, (2009) (PubMed).
: "Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5." in: International journal of colorectal disease, Vol. 21, Issue 2, pp. 130-4, (2006) (PubMed).
: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).
: "Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene." in: Gene, Vol. 278, Issue 1-2, pp. 185-92, (2001) (PubMed).
Synonyms and alternative names related to ACSL5
acyl-CoA synthetase long chain family member 5 (ACSL5), acyl-CoA synthetase long chain family member 5 (acsl5), acyl-CoA synthetase long chain family member 5 (Acsl5), acyl-CoA synthetase long-chain family member 5 (Acsl5), acyl-CoA synthetase long-chain family member 5 (ACSL5), 1700030F05Rik, acs2, ACS2, acs5, ACS5, Acs5, ACSL5, facl5, FACL5, Facl5, zgc:92083Protein level used designations for ACSL5
- acyl-CoA synthetase long-chain family member 5
- long-chain-fatty-acid--CoA ligase 5
- acyl-CoA synthetase 5
- long-chain-fatty-acid--CoA ligase 5-like
- FACL5 for fatty acid coenzyme A ligase 5
- LACS 5
- fatty acid coenzyme A ligase 5
- fatty-acid-Coenzyme A ligase, long-chain 5
- long-chain acyl-CoA synthetase 5
- long-chain fatty acid coenzyme A ligase 5
- fatty acid Coenzyme A ligase, long chain 5
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