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Acsl3 Products

(Acyl-CoA Synthetase Long-Chain Family Member 3 (Acsl3))

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The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured Acsl3 Categories

Acsl3 Antibodies

High quality antibodies with extensive validation data.

Acsl3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Acsl3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN6136456
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (4)
Cat. No. ABIN7255720
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN560840
Quantity 50 μL
Datasheet Datasheet

Recommended Acsl3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960607
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN419349
Quantity 96 tests
Datasheet Datasheet

Recommended Acsl3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305713
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305712
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3111290
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Acsl3 products

Nchoutmboube, Viktorova, Scott, Ford, Pei, Watkins, Ernst, Belov: "Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles." in: PLoS pathogens, Vol. 9, Issue 6, pp. e1003401, (2013) (PubMed).

Kassan, Herms, Fernández-Vidal, Bosch, Schieber, Reddy, Fajardo, Gelabert-Baldrich, Tebar, Enrich, Gross, Parton, Pol: "Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains." in: The Journal of cell biology, Vol. 203, Issue 6, pp. 985-1001, (2013) (PubMed).

Weedon-Fekjaer, Dalen, Solaas, Staff, Duttaroy, Nebb: "Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells." in: Journal of lipid research, Vol. 51, Issue 7, pp. 1886-96, (2010) (PubMed).

Minekura, Kang, Inagaki, Suzuki, Sato, Fujino, Yamamoto: "Genomic organization and transcription units of the human acyl-CoA synthetase 3 gene." in: Gene, Vol. 278, Issue 1-2, pp. 185-92, (2001) (PubMed).

Minekura, Fujino, Kang, Fujita, Endo, Yamamoto: "Human acyl-coenzyme A synthetase 3 cDNA and localization of its gene (ACS3) to chromosome band 2q34-q35." in: Genomics, Vol. 42, Issue 1, pp. 180-1, (1997) (PubMed).

Fujino, Kang, Suzuki, Iijima, Yamamoto: "Molecular characterization and expression of rat acyl-CoA synthetase 3." in: The Journal of biological chemistry, Vol. 271, Issue 28, pp. 16748-52, (1996) (PubMed).

Rose, King, Summers, Palmer, Yang, Wilkie, Reardon, Malcolm, Winter: "Localization of the genetic locus for Saethre-Chotzen syndrome to a 6 cM region of chromosome 7 using four cases with apparently balanced translocations at 7p21.2." in: Human molecular genetics, Vol. 3, Issue 8, pp. 1405-8, (1995) (PubMed).

Brueton, van Herwerden, Chotai, Winter: "The mapping of a gene for craniosynostosis: evidence for linkage of the Saethre-Chotzen syndrome to distal chromosome 7p." in: Journal of medical genetics, Vol. 29, Issue 10, pp. 681-5, (1992) (PubMed).

Synonyms and alternative names related to Acsl3

acyl-CoA synthetase long-chain family member 3 (ACSL3), acyl-CoA synthetase long chain family member 3 (ACSL3), acyl-CoA synthetase long chain family member 3b (acsl3b), acyl-CoA synthetase long chain family member 3a (acsl3a), AcsL3 (acsL3), acyl-CoA synthetase long-chain family member 3 (acsl3), acyl-CoA synthetase long-chain family member 3 (Acsl3), AMP-dependent synthetase and ligase family protein (LACS3), 2610510B12Rik, ACS3, Acs3, ACSL3, acsl3, C85929, F15H21.7, F15H21_7, fa07a08, FACL3, Facl3, im:7155129, long-chain acyl-CoA synthetase 3, PRO2194, Pro2194, si:dkey-20f20.5, si:dkeyp-109h9.2, wu:fa07a08, wu:fb34c03

Protein level used designations for Acsl3

  • acyl-CoA synthetase long-chain family member 3
  • AcsL3
  • LACS 3
  • long-chain acyl-CoA synthetase 3
  • long-chain-fatty-acid--CoA ligase 3
  • long-chain-fatty-acid--CoA ligase 3-like
  • fatty-acid-Coenzyme A ligase, long-chain 3
  • lignoceroyl-CoA synthase
  • fatty acid Coenzyme A ligase, long chain 3
  • brain acyl-CoA synthetase II
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