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ACO2 Products

(Aconitase 2, Mitochondrial (ACO2))

Categories

The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15), also known as Lon protease, after oxidative modification. [provided by RefSeq, Jul 2008].

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Featured ACO2 Categories

ACO2 Antibodies

High quality antibodies with extensive validation data.

ACO2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ACO2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ACO2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (7)
Cat. No. ABIN1678537
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (5)
  • (4)
Cat. No. ABIN388648
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN391809
Quantity 400 μL
Datasheet Datasheet

Recommended ACO2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964545
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964544
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964543
Quantity 96 tests
Datasheet Datasheet

Recommended ACO2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305654
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305656
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Baculovirus infected Insect Cells
Validations
  • (1)
Cat. No. ABIN7320070
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our ACO2 products

Ruiz, Bégou, Launay, Ranea-Robles, Bianchi, López-Erauskin, Morató, Guilera, Petit, Vaurs-Barriere, Guéret-Gonthier, Bonnet-Dupeyron, Fourcade, Auwerx, Boespflug-Tanguy, Pujol: "Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease." in: Brain pathology (Zurich, Switzerland), (2017) (PubMed).

Navarro, Botella, Metzendorf, Lind, Schneuwly: "Mitoferrin modulates iron toxicity in a Drosophila model of Friedreich?s ataxia." in: Free radical biology & medicine, Vol. 85, pp. 71-82, (2015) (PubMed).

Carpenter, Paw, Dewhirst, Lo: "Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells." in: Oncogene, Vol. 34, Issue 5, pp. 546-57, (2015) (PubMed).

Fernandes, Uytterhoeven, Kuenen, Wang, Slabbaert, Swerts, Kasprowicz, Aerts, Verstreken: "Reduced synaptic vesicle protein degradation at lysosomes curbs TBC1D24/sky-induced neurodegeneration." in: The Journal of cell biology, Vol. 207, Issue 4, pp. 453-62, (2014) (PubMed).

Ilgen, Stoldt, Conradi, Wurm, Rüschoff, Ghadimi, Liersch, Jakobs: "STED super-resolution microscopy of clinical paraffin-embedded human rectal cancer tissue." in: PLoS ONE, Vol. 9, Issue 7, pp. e101563, (2014) (PubMed).

Schauer, Freund, Prenni, Curthoys: "Proteomic profiling and pathway analysis of the response of rat renal proximal convoluted tubules to metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 305, Issue 5, pp. F628-40, (2013) (PubMed).

Freund, Prenni, Curthoys: "Response of the mitochondrial proteome of rat renal proximal convoluted tubules to chronic metabolic acidosis." in: American journal of physiology. Renal physiology, Vol. 304, Issue 2, pp. F145-55, (2013) (PubMed).

Tammineni, Anugula, Mohammed, Anjaneyulu, Larner, Sepuri: "The import of the transcription factor STAT3 into mitochondria depends on GRIM-19, a component of the electron transport chain." in: The Journal of biological chemistry, Vol. 288, Issue 7, pp. 4723-32, (2013) (PubMed).

Scheving, Wittig, Heide, Albuquerque, Steger, Brandt, Tegeder: "Protein S-nitrosylation and denitrosylation in the mouse spinal cord upon injury of the sciatic nerve." in: Journal of proteomics, Vol. 75, Issue 13, pp. 3987-4004, (2012) (PubMed).

Cantu, Fulton, Drechsel, Patel: "Mitochondrial aconitase knockdown attenuates paraquat-induced dopaminergic cell death via decreased cellular metabolism and release of iron and H₂O₂." in: Journal of neurochemistry, Vol. 118, Issue 1, pp. 79-92, (2011) (PubMed).

Synonyms and alternative names related to ACO2

aconitase 2 (ACO2), aconitase 2 S homeolog (aco2.S), aconitate hydratase, mitochondrial (Bm1_07420), aconitase, mitochondrial (aco2), mitochondrial aconitate hydratase (ach1), aconitase 2 (aco2), aconitase 2, mitochondrial (Aco2), aconitase 2 (Aco2), aconitase 2, mitochondrial (aco2), Probable aconitate hydratase, mitochondrial (aco-2), Aco-2, Aco3, aconitase 2, ACONM, cb1017, D10Wsu183e, DDBDRAFT_0206187, DDBDRAFT_0230168, DDB_0206187, DDB_0230168, F10M23.310, F10M23_310, ICRD, wu:fa10e03, wu:fb69g04, wu:fc20c11

Protein level used designations for ACO2

  • aconitate hydratase, mitochondrial
  • mitochondrial aconitate hydratase
  • aconitase 2, mitochondrial
  • aconitate hydratase, mitochondrial-like
  • citrate hydro-lyase
  • mitochondrial aconitase (nuclear aco2 gene)
  • heart aconitase
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