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ACIN1 Products

(Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

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Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011].

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Featured ACIN1 Categories

ACIN1 Antibodies

High quality antibodies with extensive validation data.

ACIN1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ACIN1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7242797
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, ICC, DB
Validations
  • (2)
Cat. No. ABIN930986
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, EIA
Validations
  • (3)
Cat. No. ABIN499199
Quantity 0.1 mg
Datasheet Datasheet

Recommended ACIN1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305644
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our ACIN1 products

Zheng, Schickling, Peter, Lenardo: "The death effector domain-associated factor plays distinct regulatory roles in the nucleus and cytoplasm." in: The Journal of biological chemistry, Vol. 276, Issue 34, pp. 31945-52, (2001) (PubMed).

Stoss, Schwaiger, Cooper, Stamm: "Alternative splicing determines the intracellular localization of the novel nuclear protein Nop30 and its interaction with the splicing factor SRp30c." in: The Journal of biological chemistry, Vol. 274, Issue 16, pp. 10951-62, (1999) (PubMed).

Combadiere, Gao, Tiffany, Murphy: "Gene cloning, RNA distribution, and functional expression of mCX3CR1, a mouse chemotactic receptor for the CX3C chemokine fractalkine." in: Biochemical and biophysical research communications, Vol. 253, Issue 3, pp. 728-32, (1999) (PubMed).

García, Marcos-Gutiérrez, del Mar Lorente, Moreno, Vidal: "RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1." in: The EMBO journal, Vol. 18, Issue 12, pp. 3404-18, (1999) (PubMed).

Zamzami, Kroemer: "Condensed matter in cell death." in: Nature, Vol. 401, Issue 6749, pp. 127-8, (1999) (PubMed).

Combadiere, Ahuja, Murphy: "Cloning, chromosomal localization, and RNA expression of a human beta chemokine receptor-like gene." in: DNA and cell biology, Vol. 14, Issue 8, pp. 673-80, (1995) (PubMed).

Raport, Schweickart, Eddy, Shows, Gray: "The orphan G-protein-coupled receptor-encoding gene V28 is closely related to genes for chemokine receptors and is expressed in lymphoid and neural tissues." in: Gene, Vol. 163, Issue 2, pp. 295-9, (1995) (PubMed).

Harrison, Barber, Lynch: "cDNA cloning of a G-protein-coupled receptor expressed in rat spinal cord and brain related to chemokine receptors." in: Neuroscience letters, Vol. 169, Issue 1-2, pp. 85-9, (1994) (PubMed).

Synonyms and alternative names related to ACIN1

apoptotic chromatin condensation inducer 1b (acin1b), apoptotic chromatin condensation inducer 1a (acin1a), apoptotic chromatin condensation inducer 1 (acin1), apoptotic chromatin condensation inducer 1 (ACIN1), apoptotic chromatin condensation inducer 1 S homeolog (acin1.S), apoptotic chromatin condensation inducer 1 (Acin1), 2610036I19Rik, 2610510L13Rik, acinus, ACINUS, Acinus, acinusa, acinusb, acinusl, acinusL, acinusS, acn, ACN, Acn, C79325, fi14c05, fSAP152, ik:tdsubc_2g5, mKIAA0670, si:zc14a17.12, wu:fb04g06, wu:fb40f03, wu:fb68h03, wu:fb80f07, wu:fc12e10, wu:fe06a10, wu:fi14c05, xx:tdsubc_2g5

Protein level used designations for ACIN1

  • apoptotic chromatin condensation inducer in the nucleus, b
  • apoptotic chromatin condensation inducer in the nucleus, a
  • apoptotic chromatin condensation inducer 1
  • apoptotic chromatin condensation inducer in the nucleus
  • apoptotic chromatin condensation inducer in the nucleus-like
  • functional spliceosome-associated protein 152
  • acinus
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