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Acetylated Lysine Antibodies

(Acetylated Lysine)
This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008].

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Latest Publications for our Acetylated Lysine products

Zhou, Huang, Zhang, Zhao, Kim, Tu, Zhang, Nowsheen, Zhu, Deng, Chen, Qin, Luo, Liu, Lou, Mutter, Yuan: "The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair." in: Nature communications, Vol. 11, Issue 1, pp. 2639, (2020) (PubMed).

Dziewulska, Dobosz, Dobrzyn, Smolinska, Kolczynska, Ntambi, Dobrzyn: "SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle." in: Journal of cellular physiology, (2019) (PubMed).

Tataranni, Agriesti, Ruggieri, Mazzoccoli, Simeon, Laurenzana, Scrima, Pazienza, Capitanio, Piccoli: "Rewiring carbohydrate catabolism differentially affects survival of pancreatic cancer cell lines with diverse metabolic profiles." in: Oncotarget, Vol. 8, Issue 25, pp. 41265-41281, (2018) (PubMed).

Lin, Yuan, Pei, Liu, Ann, Lou: "KAP1 Deacetylation by SIRT1 Promotes Non-Homologous End-Joining Repair." in: PLoS ONE, Vol. 10, Issue 4, pp. e0123935, (2016) (PubMed).

Wu, Chen, Lu, Zhang, Zhang, Duan, Wang, Huang, Kang: "Acetylation-dependent function of human single-stranded DNA binding protein 1." in: Nucleic acids research, Vol. 43, Issue 16, pp. 7878-87, (2015) (PubMed).

Koen, Sarma, Hajovsky, Galeva, Williams, Staudinger, Hanzlik: "Protein targets of thioacetamide metabolites in rat hepatocytes." in: Chemical research in toxicology, Vol. 26, Issue 4, pp. 564-74, (2014) (PubMed).

Pérez-Luna, Aguasca, Perearnau, Serratosa, Martínez-Balbas, Jesús Pujol, Bachs: "PCAF regulates the stability of the transcriptional regulator and cyclin-dependent kinase inhibitor p27 Kip1." in: Nucleic acids research, Vol. 40, Issue 14, pp. 6520-33, (2012) (PubMed).

Yang: "Multisite protein modification and intramolecular signaling." in: Oncogene, Vol. 24, Issue 10, pp. 1653-62, (2005) (PubMed).

Yang: "Lysine acetylation and the bromodomain: a new partnership for signaling." in: BioEssays : news and reviews in molecular, cellular and developmental biology, Vol. 26, Issue 10, pp. 1076-87, (2004) (PubMed).

Vigushin, Coombes: "Targeted histone deacetylase inhibition for cancer therapy." in: Current cancer drug targets, Vol. 4, Issue 2, pp. 205-18, (2004) (PubMed).

Synonyms and alternative names related to Acetylated Lysine

KRAS proto-oncogene, GTPase (KRAS), C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, KI-RAS, KRAS1, KRAS2, NS, NS3, RASK2

Protein level used designations for Acetylated Lysine

  • GTPase KRas
  • K-Ras 2
  • K-ras p21 protein
  • PR310 c-K-ras oncogene
  • c-Ki-ras
  • c-Kirsten-ras protein
  • cellular c-Ki-ras2 proto-oncogene
  • oncogene KRAS2
  • transforming protein p21
  • v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog
  • v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
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