ACER1 Products
(Alkaline Ceramidase 1 (ACER1))
Categories
Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic signals and induce apoptosis, and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules. Ceramide hydrolysis in the nucleated cell layers regulates keratinocyte proliferation and apoptosis in response to external stress. Ceramide hydrolysis also occurs at the stratum corneum, releasing free sphingoid base that functions as an endogenous antimicrobial agent. ACER1 is highly expressed in epidermis and catalyzes the hydrolysis of very long chain ceramides to generate sphingosine (Houben et al., 2006 [PubMed 16477081]\; Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010].
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Featured ACER1 Categories
ACER1 Antibodies
High quality antibodies with extensive validation data.
ACER1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ACER1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6260068
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7185928
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
Cat. No.
ABIN1536908
Quantity
400 μL
Datasheet
Datasheet
Recommended ACER1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3104294
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3126824
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2714568
Quantity
20 μg
Datasheet
Datasheet
Synonyms and alternative names related to ACER1
alkaline ceramidase 1 (ACER1), alkaline ceramidase 1 (acer1), alkaline ceramidase 1 (Acer1), 2310024P18Rik, AI662009, ALKCDase1, Alkcdase1, ASAH3, asah3, Asah3, Cer1, zgc:110285Protein level used designations for ACER1
- N-acylsphingosine amidohydrolase (alkaline ceramidase) 3
- alkaline ceramidase 1
- N-acylsphingosine amidohydrolase 3
- acylsphingosine deacylase 3
- alkCDase 1
- alkaline CDase 1
- alkaline cdase 1
- maCER1
Did you look for something else?
- ACEI
- ACE2
- ACD1
- ACD
- ACCSL
- ACCN5
- ACCN4
- ACCN1
- ACCD6
- ACC Synthase 7
- ACBD7
- ACBD6
- ACBD5
- ACBD4
- ACBD3
- ACAT2
- ACAT1
- Acap3
- ACAP1
- ACADVL
- ACER2
- ACER3
- Acetate Kinase
- Acetoin Reductase
- Acetyl-CoA
- Acetyl-CoA Carboxylase
- Acetyl-CoA Carboxylase alpha
- Acetyl-CoA Carboxylase beta
- Acetylated Lysine
- Acetylcholine
- Acetylcholinesterase
- Achaete
- Achaete-Scute Complex Homolog 1 (Drosophila)
- Achaete-scute complex protein T5
- ACHB3
- AChR Ab
- Acid Invertase
- Acid Phosphatase
- ACIN1
- ACLY
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