ABCG5 Products
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 5 (ABCG5))
Categories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
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Featured ABCG5 Categories
ABCG5 Antibodies
High quality antibodies with extensive validation data.
ABCG5 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ABCG5 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (2)
- (7)
Cat. No.
ABIN1724857
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
Cat. No.
ABIN7144938
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p)
Validations
- (2)
- (3)
Cat. No.
ABIN708371
Quantity
100 μL
Datasheet
Datasheet
Recommended ABCG5 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419754
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3118046
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3128146
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ABCG5 products
: "Role of Baicalin and Liver X Receptor Alpha in the Formation of Cholesterol Gallstones in Mice." in: Gastroenterology research and practice, Vol. 2020, pp. 1343969, (2020) (PubMed).: "Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease." in: The Korean journal of internal medicine, (2018) (PubMed).
: "Microbiota prevents cholesterol loss from the body by regulating host gene expression in mice." in: Scientific reports, Vol. 5, pp. 10512, (2015) (PubMed).
: "Chronic unpredictable mild stress combined with a high-fat diets aggravates atherosclerosis in rats." in: Lipids in health and disease, Vol. 13, pp. 77, (2014) (PubMed).
: "Expression of liver X receptor correlates with intrahepatic inflammation and fibrosis in patients with nonalcoholic fatty liver disease." in: Digestive diseases and sciences, Vol. 59, Issue 12, pp. 2975-82, (2014) (PubMed).
: "Lactobacillus acidophilus ATCC 4356 prevents atherosclerosis via inhibition of intestinal cholesterol absorption in apolipoprotein E-knockout mice." in: Applied and environmental microbiology, Vol. 80, Issue 24, pp. 7496-504, (2014) (PubMed).
: "ATP-binding cassette transporter G5 and G8 polymorphisms and several environmental factors with serum lipid levels." in: PLoS ONE, Vol. 7, Issue 5, pp. e37972, (2012) (PubMed).
: "ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis." in: Journal of lipid research, Vol. 51, Issue 10, pp. 3016-23, (2010) (PubMed).
: "Bile acids stimulate ATP hydrolysis in the purified cholesterol transporter ABCG5/G8." in: Biochemistry, Vol. 49, Issue 16, pp. 3403-11, (2010) (PubMed).
: "Identification of a gene, ABCG5, important in the regulation of dietary cholesterol absorption." in: Nature genetics, Vol. 27, Issue 1, pp. 79-83, (2001) (PubMed).
Synonyms and alternative names related to ABCG5
ATP binding cassette subfamily G member 5 (ABCG5), ATP-binding cassette, sub-family G (WHITE), member 5 (abcg5), ABC transporter G family protein (abcG5), ATP binding cassette subfamily G member 5 (abcg5), ATP-binding cassette, sub-family G (WHITE), member 5 (ABCG5), ATP binding cassette subfamily G member 5 (Abcg5), AW112016, cmp, DDBDRAFT_0205617, DDBDRAFT_0215344, DDB_0205617, DDB_0215344, sterolin-1, STSL, tracProtein level used designations for ABCG5
- ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1)
- ATP-binding cassette sub-family G member 5
- sterolin 1
- ATP-binding cassette transporter
- ATP-binding cassette, sub-family G (WHITE), member 5
- ATP-binding cassette sub-family G member 5-like
- ATP-binding cassette, subfamily G, member 5
- sterolin-1
- ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1)
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