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ABCE1 Products

(ATP-Binding Cassette, Sub-Family E (OABP), Member 1 (ABCE1))

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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured ABCE1 Categories

ABCE1 Antibodies

High quality antibodies with extensive validation data.

ABCE1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ABCE1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7144924
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7265739
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7235706
Quantity 200 μL
Datasheet Datasheet

Recommended ABCE1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6212481
Quantity 96 tests
Datasheet Datasheet

Recommended ABCE1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN7489119
Quantity 2 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1305481
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3088322
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our ABCE1 products

Wu, Wang, Lim, Liu, Li, Vartak, Stankiewicz, Montgomery, Lu: "Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy." in: Cell metabolism, Vol. 28, Issue 1, pp. 130-144.e7, (2019) (PubMed).

Toompuu, Kärblane, Pata, Truve, Sarmiento: "ABCE1 is essential for S phase progression in human cells." in: Cell cycle (Georgetown, Tex.), Vol. 15, Issue 9, pp. 1234-47, (2016) (PubMed).

Desmet, Anguish, Parker: "Virus-mediated compartmentalization of the host translational machinery." in: mBio, Vol. 5, Issue 5, pp. e01463-14, (2015) (PubMed).

Fabre, Breuker, Amouzou, Salehzada, Kitzmann, Mercier, Bisbal: "Defects in TLR3 expression and RNase L activation lead to decreased MnSOD expression and insulin resistance in muscle cells of obese people." in: Cell death & disease, Vol. 5, pp. e1136, (2014) (PubMed).

Chen, Dong, Ishimura, Daar, Hinnebusch, Dean: "The essential vertebrate ABCE1 protein interacts with eukaryotic initiation factors." in: The Journal of biological chemistry, Vol. 281, Issue 11, pp. 7452-7, (2006) (PubMed).

Shichijo, Ishihara, Azuma, Komatsu, Higashimoto, Ito, Nakamura, Ueno, Harada, Itoh: "ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients." in: Oncology reports, Vol. 13, Issue 5, pp. 907-13, (2005) (PubMed).

Synonyms and alternative names related to ABCE1

ATP binding cassette subfamily E member 1 (ABCE1), 4Fe-4S ferredoxin, iron-sulfur binding domain-containing protein (abcE1), ATP-binding cassette sub-family E member 1 (LOC100184673), ATP-binding cassette sub-family E member 1 (LOC100213121), ATP binding cassette subfamily E member 1 (abce1), RNAse L inhibitor (TP04_0855), RNase L inhibitor (PVX_115370), ribosome biogenesis/translation initiation ATPase RLI (TERMP_RS03360), ATP-binding cassette, sub-family E (OABP), member 1 (Abce1), ATP-binding cassette, sub-family E (OABP), member 1 (abce1), ATP binding cassette subfamily E member 1 S homeolog (abce1.S), ATP binding cassette subfamily E member 1 (Abce1), ABC38, ABCE1, abce1, C79080, DDBDRAFT_0188931, DDBDRAFT_0191227, DDB_0188931, DDB_0191227, DKFZp469K1416, MGC69546, OABP, Oabp, RLI, RNASEL1, RNASELI, Rnaseli, RNS4I, Rns4i, RNS41, wu:fb34c09, wu:fe47b01, wu:fi09g07, zgc:56045, zgc:111906

Protein level used designations for ABCE1

  • ATP-binding cassette, sub-family E (OABP), member 1
  • ABC transporter-related protein
  • RNaseL inhibitor-like protein
  • ATP-binding cassette, sub-family E, member 1
  • ATP-binding cassette sub-family E member 1-like
  • RNAse L inhibitor
  • RNase L inhibitor
  • 2'-5'-oligoadenylate-binding protein
  • ATP-binding cassette sub-family E member 1
  • huHP68
  • ribonuclease 4 inhibitor
  • ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) inhibitor
  • ATP-binding cassette, subfamily E, member 1
  • RNS4I
  • RNS4l (Eye)
  • ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor
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