ABCD4 Products
(ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4))
Categories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding. [provided by RefSeq, Jul 2008].
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Featured ABCD4 Categories
ABCD4 Antibodies
High quality antibodies with extensive validation data.
ABCD4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ABCD4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, ICC, IF
Validations
- (3)
Cat. No.
ABIN6257921
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN335110
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (4)
Cat. No.
ABIN5013197
Quantity
100 μL
Datasheet
Datasheet
Recommended ABCD4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3109592
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3132293
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN6239310
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our ABCD4 products
: "Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism. ..." in: Nature genetics, Vol. 44, Issue 10, pp. 1152-5, (2012) (PubMed).: "Decreased expression of ABCD4 and BG1 genes early in the pathogenesis of X-linked adrenoleukodystrophy." in: Human molecular genetics, Vol. 14, Issue 10, pp. 1293-303, (2005) (PubMed).
Synonyms and alternative names related to ABCD4
ATP binding cassette subfamily D member 4 (ABCD4), ATP binding cassette subfamily D member 4 (Abcd4), ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4), ATP-binding cassette, sub-family D (ALD), member 4 (abcd4), ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4), ABC41, ABCD4, EST352188, MAHCJ, P69r, P70R, P79R, PMP69, PXMP1L, Pxmp1l, zgc:153503Protein level used designations for ABCD4
- 69 kDa peroxisomal ABC-transporter
- ATP-binding cassette sub-family D member 4
- PMP70-related protein
- PXMP1-L
- peroxisomal membrane protein 69
- ATP-binding cassette, sub-family D (ALD), member 4
- ATP-binding cassette, sub-family D, member 4
- PMP69
- peroxisomal membrane protein, 70 kDa-related
- ATP-binding cassette sub-family D member 4-like
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