ABCC4 Products
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))
Categories
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined\; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Featured ABCC4 Categories
ABCC4 Antibodies
High quality antibodies with extensive validation data.
ABCC4 ELISA Kits
Reliable ELISA kits for a wide range of species.
ABCC4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ABCC4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (1)
- (6)
Cat. No.
ABIN1724860
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC
Validations
- (4)
- (4)
Cat. No.
ABIN185302
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (4)
Cat. No.
ABIN564442
Quantity
100 μg
Datasheet
Datasheet
Recommended ABCC4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965075
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953982
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5652072
Quantity
96 tests
Datasheet
Datasheet
Recommended ABCC4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305457
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407946
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3109892
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ABCC4 products
: "Sensitizing gastric adenocarcinoma to chemotherapy by pharmacological manipulation of drug transporters." in: Biochemical pharmacology, Vol. 171, pp. 113682, (2020) (PubMed).: "The Origin of Follicular Bile Acids in the Human Ovary." in: The American journal of pathology, (2019) (PubMed).
: "Stable knock-down of efflux transporters leads to reduced glucuronidation in UGT1A1-overexpressing HeLa cells: the evidence for glucuronidation-transport interplay." in: Molecular pharmaceutics, Vol. 12, Issue 4, pp. 1268-78, (2016) (PubMed).
: "Efflux transport of chrysin and apigenin sulfates in HEK293 cells overexpressing SULT1A3: The role of multidrug resistance-associated protein 4 (MRP4/ABCC4)." in: Biochemical pharmacology, Vol. 98, Issue 1, pp. 203-14, (2016) (PubMed).
: "Characterization of chrysin glucuronidation in UGT1A1-overexpressing HeLa cells: elucidating the transporters responsible for efflux of glucuronide." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 43, Issue 4, pp. 433-43, (2015) (PubMed).
: "Essential role of vesicular nucleotide transporter in vesicular storage and release of nucleotides in platelets." in: Physiological reports, Vol. 2, Issue 6, (2014) (PubMed).
: "HEK-293 cells expressing the cystic fibrosis transmembrane conductance regulator (CFTR): a model for studying regulation of Cl- transport." in: Physiological reports, Vol. 2, Issue 9, (2014) (PubMed).
: "Augmented epithelial multidrug resistance-associated protein 4 expression in peritoneal endometriosis: regulation by lipoxin A(4)." in: Fertility and sterility, Vol. 99, Issue 7, pp. 1965-73.e2, (2013) (PubMed).
: "Multidrug resistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression." in: Virchows Archiv : an international journal of pathology, Vol. 462, Issue 4, pp. 437-43, (2013) (PubMed).
: "Monoclonal antibodies to discriminate the EF hand containing calcium binding adaptor proteins EFhd1 and EFhd2." in: Monoclonal antibodies in immunodiagnosis and immunotherapy, Vol. 32, Issue 4, pp. 237-45, (2013) (PubMed).
Synonyms and alternative names related to ABCC4
ATP binding cassette subfamily C member 4 (ABCC4), multidrug resistance-associated protein 4 (LOC515333), multidrug resistance-associated protein 4 (LOC616707), multidrug resistance-associated protein 4 (LOC695407), ATP binding cassette subfamily C member 4 (abcc4), ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), ATP binding cassette subfamily C member 4 (Abcc4), D630049P08Rik, EST170205, MOAT-B, MOATB, MRP4, Mrp4Protein level used designations for ABCC4
- multidrug resistance-associated protein 4
- ATP-binding cassette, sub-family C (CFTR/MRP), member 4
- ATP-binding cassette protein C4-like
- multidrug resistance-associated protein 4-like
- ATP-binding cassette sub-family C member 4
- MRP/cMOAT-related ABC transporter
- bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4)
- canalicular multispecific organic anion transporter (ABC superfamily)
- multi-specific organic anion transporter B
- multispecific organic anion transporter B
- ABC-tranporter
- ATP-binding cassette protein C4
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