ABCC1 Products
(ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))
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The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012].
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Featured ABCC1 Categories
ABCC1 Antibodies
High quality antibodies with extensive validation data.
ABCC1 ELISA Kits
Reliable ELISA kits for a wide range of species.
ABCC1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ABCC1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7440026
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IF
Validations
- (5)
Cat. No.
ABIN3017211
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, ELISA
Validations
- (1)
- (2)
Cat. No.
ABIN6266183
Quantity
100 μL
Datasheet
Datasheet
Recommended ABCC1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965071
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965072
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953975
Quantity
96 tests
Datasheet
Datasheet
Recommended ABCC1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305446
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7411681
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7393115
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ABCC1 products
: "Acetazolamide Suppresses Multi-Drug Resistance-Related Protein 1 and P-Glycoprotein Expression by Inhibiting Aquaporins Expression in a Mesial Temporal Epilepsy Rat Model." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 5818-5825, (2018) (PubMed).: "Characteristics of doxorubicin-selected multidrug-resistant human leukemia HL-60 cells with tolerance to arsenic trioxide and contribution of leukemia stem cells." in: Oncology letters, Vol. 15, Issue 1, pp. 1255-1262, (2018) (PubMed).
: "miR-506 enhances the sensitivity of human colorectal cancer cells to oxaliplatin by suppressing MDR1/P-gp expression." in: Cell proliferation, Vol. 50, Issue 3, (2017) (PubMed).
: "Cycloartenyl Ferulate Inhibits Paraquat-Induced Apoptosis in HK-2 Cells With the Involvement of ABCC1." in: Journal of cellular biochemistry, Vol. 117, Issue 4, pp. 872-80, (2016) (PubMed).
: "Enhanced combination therapy effect on paclitaxel-resistant carcinoma by chloroquine co-delivery via liposomes." in: International journal of nanomedicine, Vol. 10, pp. 6615-32, (2016) (PubMed).
: "Enhanced autophagy reveals vulnerability of P-gp mediated epirubicin resistance in triple negative breast cancer cells." in: Apoptosis : an international journal on programmed cell death, Vol. 21, Issue 4, pp. 473-88, (2016) (PubMed).
: "Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes." in: Biomaterials, Vol. 34, Issue 18, pp. 4452-65, (2013) (PubMed).
: "The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats." in: Environmental toxicology and pharmacology, Vol. 35, Issue 1, pp. 109-16, (2013) (PubMed).
: "Mechanistic analysis of taxol-induced multidrug resistance in an ovarian cancer cell line." in: Asian Pacific journal of cancer prevention : APJCP, Vol. 14, Issue 9, pp. 4983-8, (2013) (PubMed).
: "Multidrug-resistance-associated protein plays a protective role in menadione-induced oxidative stress in endothelial cells." in: Life sciences, Vol. 84, Issue 7-8, pp. 211-7, (2009) (PubMed).
Synonyms and alternative names related to ABCC1
ATP binding cassette subfamily C member 1 (ABCC1), ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1), ATP binding cassette subfamily C member 1 (Abcc1), multidrug resistance-associated protein 1 (LOC100152428), multidrug resistance-associated protein 1 (LOC100346553), ABC29, ABCC, Abcc1a, Abcc1b, ABCC13, Avcc1a, GS-X, Mdrap, MRP, Mrp, MRP1, Mrp1Protein level used designations for ABCC1
- ATP-binding cassette transporter variant ABCC1delta-ex13
- ATP-binding cassette transporter variant ABCC1delta-ex13&14
- ATP-binding cassette transporter variant ABCC1delta-ex25
- ATP-binding cassette transporter variant ABCC1delta-ex25&26
- LTC4 transporter
- leukotriene C(4) transporter
- multidrug resistance-associated protein 1
- ATP-binding cassette sub-family C member 1
- multidrug resistance protein 1
- ATP-binding cassette, sub-family C (CFTR/MRP), member 1a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 1b
- multiple drug resistance-associated protein
- ATP-binding cassette sub-family C ( CFTR/MRP) member 1a
- ATP-binding cassette, sub-family C (CFTR/MRP), member 1
- ATP-binding cassette superfamily member C1
- ATP-binding cassette transporter sub-family C member 1
- ATP-binding cassette, sub-family C, member 1
- multiple drug resistance protein 1
- ATP-binding cassette, sub-family C (CFTR/MRP), member 13
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