ABAT Products
(4-Aminobutyrate Aminotransferase (ABAT))
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4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured ABAT Categories
ABAT Antibodies
High quality antibodies with extensive validation data.
ABAT Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ABAT Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7445057
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, ICC, IHC (fro)
Validations
- (6)
Cat. No.
ABIN2854765
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (1)
- (5)
Cat. No.
ABIN6136330
Quantity
100 μL
Datasheet
Datasheet
Recommended ABAT ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6211646
Quantity
96 tests
Datasheet
Datasheet
Recommended ABAT Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1774924
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419613
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419616
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ABAT products
: "Proteomics and metabolomics analysis of hepatic mitochondrial metabolism in alcohol-preferring and non-preferring rats." in: Oncotarget, Vol. 8, Issue 60, pp. 102020-102032, (2017) (PubMed).: "Liver protein profiling in chronic hepatitis C: identification of potential predictive markers for interferon therapy outcome." in: Journal of proteome research, Vol. 11, Issue 2, pp. 717-27, (2012) (PubMed).
Synonyms and alternative names related to ABAT
4-aminobutyrate aminotransferase (ABAT), 4-aminobutyrate aminotransferase (abat), 4-aminobutyrate--2-oxoglutarate transaminase (gabT), GABA aminotransferase PLP-dependent PuuE (puuE), 4-aminobutyrate aminotransferase (gabT-1), 4-aminobutyrate aminotransferase (gabT-2), 4-aminobutyrate aminotransferase (gabT-3), 4-aminobutyrate aminotransferase (gabT), 4-aminobutyrate aminotransferase (CNE01830), 4-aminobutyrate aminotransferase (Mmwyl1_0047), 4-aminobutyrate aminotransferase, mitochondrial (CpipJ_CPIJ008729), aspartate aminotransferase family protein (KCR_RS04555), 4-aminobutyrate aminotransferase (Bcenmc03_4909), 4-aminobutyrate aminotransferase (Hden_0972), 4-aminobutyrate aminotransferase (Dbac_2000), 4-aminobutyrate aminotransferase (Mesil_2400), 4-aminobutyrate aminotransferase (Trad_0121), 4-aminobutyrate aminotransferase S homeolog (abat.S), 4-aminobutyrate aminotransferase (Abat), 9630038C02Rik, AI255750, BA0325, beta-AlaAT, cb880, ENSMUSG00000051226, fj82a01, GABA-AT, GABA-T, Gabaat, GABAT, Gabat, Gm9851, I54, L-AIBAT, Laibat, NPD009, PSPTO0259, PSPTO0301, PSPTO1890, wu:fj82a01, X61497Protein level used designations for ABAT
- 4-aminobutyrate aminotransferase, mitochondrial
- GABA-T
- 4-aminobutyrate aminotransferase
- (S)-3-amino-2-methylpropionate transaminase
- 4-aminobutyrate transaminase
- GABA aminotransferase
- GABA transaminase
- GABA transferase
- gamma-amino-N-butyrate transaminase
- GABA-AT
- L-AIBAT
- beta-alanine oxoglutarate aminotransferase
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