AAK1 Products
(AP2 associated kinase 1 (AAK1))
Categories
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and phosphorylates a subunit of the AP-2 complex, which promotes binding of AP-2 to sorting signals found in membrane-bound receptors and subsequent receptor endocytosis. Its kinase activity is stimulated by clathrin. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Featured AAK1 Categories
AAK1 Antibodies
High quality antibodies with extensive validation data.
AAK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
AAK1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended AAK1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN524804
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7144390
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IHC (p)
Validations
- (3)
Cat. No.
ABIN462517
Quantity
0.05 mg
Datasheet
Datasheet
Recommended AAK1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6964516
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN5648154
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Cow
Analytical Method
Validations
Cat. No.
ABIN1122169
Quantity
96 tests
Datasheet
Datasheet
Recommended AAK1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305397
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1305395
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3087952
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our AAK1 products
: "A novel AAK1 splice variant functions at multiple steps of the endocytic pathway." in: Molecular biology of the cell, Vol. 18, Issue 7, pp. 2698-706, (2007) (PubMed).: "Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells." in: Oncogene, Vol. 20, Issue 36, pp. 4995-5004, (2001) (PubMed).
: "Matrix detachment induces caspase-dependent cytochrome c release from mitochondria: inhibition by PKB/Akt but not Raf signalling." in: Oncogene, Vol. 19, Issue 39, pp. 4461-8, (2000) (PubMed).
Synonyms and alternative names related to AAK1
AP2 associated kinase 1 (AAK1), AP2 associated kinase 1 (Aak1), uncharacterized protein FLJ45252 (LOC100512341), AP2 associated kinase 1b (aak1b), 5530400K14Rik, 9630042K20, aak1, AU067724, AU067726, BC028270, C79663, D6Ertd245e, mKIAA1048, R75501, RGD1563580, si:dkey-261l11.5Protein level used designations for AAK1
- AP2-associated protein kinase 1
- adaptor-associated kinase 1
- AP2 associated kinase 1
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