2B4 Products
(Natural Killer Cell Receptor 2B4 (CD244))
Categories
This gene encodes a cell surface receptor expressed on natural killer (NK) cells (and some T cells) that mediate non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009].
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Featured 2B4 Categories
2B4 Antibodies
High quality antibodies with extensive validation data.
2B4 ELISA Kits
Reliable ELISA kits for a wide range of species.
2B4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended 2B4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7441829
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, ICC, IF
Validations
- (4)
Cat. No.
ABIN6260596
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN6964066
Quantity
100 μg
Datasheet
Datasheet
Recommended 2B4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965553
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1672841
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN4881695
Quantity
96 tests
Datasheet
Datasheet
Recommended 2B4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273780
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273781
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7273782
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our 2B4 products
: "Dietary Consumption of Black Raspberries or Their Anthocyanin Constituents Alters Innate Immune Cell Trafficking in Esophageal Cancer." in: Cancer immunology research, Vol. 4, Issue 1, pp. 72-82, (2016) (PubMed).: "Priming of Human Resting NK Cells by Autologous M1 Macrophages via the Engagement of IL-1β, IFN-β, and IL-15 Pathways." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2818-28, (2015) (PubMed).
: "Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation." in: Journal of hepatology, Vol. 61, Issue 6, pp. 1212-9, (2014) (PubMed).
: "Engagement of SLAMF2/CD48 prolongs the time frame of effective T cell activation by supporting mature dendritic cell survival." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 9, pp. 4436-42, (2014) (PubMed).
: "The immunoregulatory role of CD244 in chronic hepatitis B infection and its inhibitory potential on virus-specific CD8+ T-cell function." in: Hepatology (Baltimore, Md.), Vol. 52, Issue 6, pp. 1934-47, (2010) (PubMed).
: "T cell infiltrates in the muscles of patients with dermatomyositis and polymyositis are dominated by CD28null T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 7, pp. 4792-9, (2009) (PubMed).
: "Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors." in: Blood, Vol. 112, Issue 12, pp. 4494-502, (2008) (PubMed).
: "Inappropriate recruitment and activity by the Src homology region 2 domain-containing phosphatase 1 (SHP1) is responsible for receptor dominance in the SHIP-deficient NK cell." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 12, pp. 8009-15, (2007) (PubMed).
: "Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 30, pp. 11258-63, (2006) (PubMed).
: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
Synonyms and alternative names related to 2B4
CD244 molecule (CD244), CD244 molecule (Cd244), CD244 natural killer cell receptor 2B4 (Cd244), 2B4, C9.1, CD244, F730046O15Rik, Ly90, NAIL, NKR2B4, Nmrk, SLAMF4Protein level used designations for 2B4
- CD244 molecule, natural killer cell receptor 2B4
- natural killer cell receptor 2B4
- NK cell activation inducing ligand NAIL
- NK cell activation-inducing ligand
- NK cell type I receptor protein 2B4
- SLAM family member 4
- h2B4
- signaling lymphocytic activation molecule 4
- CD244 natural killer cell receptor 2B4
- NKR2B4
- non MHC restricted killing associated
- non-MHC restricted killing associated
- transmembrane NK cell receptor 2B4
- NK cell receptor 2B4
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