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14-3-3 sigma/SFN Products

(Stratifin (SFN))

Categories

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.

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Featured 14-3-3 sigma/SFN Categories

14-3-3 sigma/SFN Antibodies

High quality antibodies with extensive validation data.

14-3-3 sigma/SFN ELISA Kits

Reliable ELISA kits for a wide range of species.

14-3-3 sigma/SFN Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended 14-3-3 sigma/SFN Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF, IP, IHC (p), ICC
Validations
  • (1)
  • (18)
Cat. No. ABIN2854867
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (6)
Cat. No. ABIN185539
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IP, IHC (p)
Validations
  • (1)
  • (5)
Cat. No. ABIN561091
Quantity 100 μg
Datasheet Datasheet

Recommended 14-3-3 sigma/SFN ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6959729
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6970439
Quantity 96 tests
Datasheet Datasheet
Reactivity Chicken
Analytical Method
Validations
Cat. No. ABIN1773391
Quantity 96 tests
Datasheet Datasheet

Recommended 14-3-3 sigma/SFN Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319731
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1319729
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN1097592
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our 14-3-3 sigma/SFN products

Kim, Morales, Baek, Slaga, DiGiovanni, Kim: "UVB-induced nuclear translocation of TC-PTP by AKT/14-3-3σ axis inhibits keratinocyte survival and proliferation." in: Oncotarget, Vol. 8, Issue 53, pp. 90674-90692, (2017) (PubMed).

Chen, Chung, Wu, Ng, Yu, Tsai, Chang, Liang, Tsui, Chen: "Comparative Tissue Proteomics of Microdissected Specimens Reveals Novel Candidate Biomarkers of Bladder Cancer." in: Molecular & cellular proteomics : MCP, (2015) (PubMed).

Xu, Li, Tao, Li, Fang, Zhao, Li, Li, Wang, Feng, Pan: "Histone acetyltransferase inhibitor II induces apoptosis in glioma cell lines via the p53 signaling pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 33, pp. 108, (2015) (PubMed).

Sun, Boxer, Ransohoff, Siprashvili, Qu, Lopez-Pajares, Hollmig, Khavari: "CALML5 is a ZNF750- and TINCR-induced protein that binds stratifin to regulate epidermal differentiation." in: Genes & development, Vol. 29, Issue 21, pp. 2225-30, (2015) (PubMed).

Taurino, Stanca, Vonghia, Siculella, Sardanelli, Papa, Zanotti, Gnoni: "Short-term type-1 diabetes differentially modulates 14-3-3 proteins in rat brain and liver." in: European journal of clinical investigation, Vol. 44, Issue 4, pp. 350-8, (2014) (PubMed).

Sousa, Zub, Aas, Hanssen-Bauer, Demirovic, Sarno, Tian, Liabakk, Slupphaug: "An inverse switch in DNA base excision and strand break repair contributes to melphalan resistance in multiple myeloma cells." in: PLoS ONE, Vol. 8, Issue 2, pp. e55493, (2013) (PubMed).

Zeiler, Straube, Lundberg, Uhlen, Mann: "A Protein Epitope Signature Tag (PrEST) library allows SILAC-based absolute quantification and multiplexed determination of protein copy numbers in cell lines." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 3, pp. O111.009613, (2012) (PubMed).

Koh, Wei, Li, Huang, Doan, Scolyer, Cochran, Binder: "Differential gene expression profiling of primary cutaneous melanoma and sentinel lymph node metastases." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 25, Issue 6, pp. 828-37, (2012) (PubMed).

Lu, Zhu, Wen, Yang, Shaw, Lammer, Finnell: "Nicotinamide N-methyl transferase (NNMT) gene polymorphisms and risk for spina bifida." in: Birth defects research. Part A, Clinical and molecular teratology, Vol. 82, Issue 10, pp. 670-5, (2008) (PubMed).

Yang, Cheung, Peng, He, Wu, Xie, Jiang, Huang, Chen, Lin, Kung: "Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal." in: The Journal of biological chemistry, Vol. 283, Issue 13, pp. 8486-95, (2008) (PubMed).

Synonyms and alternative names related to 14-3-3 sigma/SFN

stratifin (SFN), stratifin (Sfn), Er, Mme1, YWHAS, Ywhas

Protein level used designations for 14-3-3 sigma/SFN

  • 14-3-3 sigma
  • 14-3-3 protein sigma
  • epithelial cell marker protein 1
  • 14-3-3 sigma protein
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, sigma polypeptide
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