PDX1 antibody
(1 reference)-
- Target See all PDX1 Antibodies
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This PDX1 antibody is un-conjugated
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Application
- ELISA, Flow Cytometry (FACS)
- Purpose
- PDX1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human PDX1 expressed in E. Coli.
- Clone
- 5A5
- Isotype
- IgG1
- Top Product
- Discover our top product PDX1 Primary Antibody
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anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-284) antibody
PDX1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 Reactivity: Human ELISA, FACS Host: Mouse Monoclonal 2G12 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-30) antibodyPDX1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-30) antibodyPDX1 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal RB15204 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 1-283) antibodyPDX1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) antibodyPDX1 Reactivity: Human WB, FACS, EIA Host: Mouse Monoclonal 5A5 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 188-284) antibodyPDX1 Reactivity: Rat, Goat WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 40-69), (N-Term) antibodyPDX1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB10459 unconjugated
anti-Pancreatic and Duodenal Homeobox 1 (PDX1) (AA 186-215), (C-Term) antibodyPDX1 Reactivity: Human WB, IF Host: Rabbit Polyclonal RB10579 unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36482-90, (2009) (PubMed).
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: "MODY7 gene, KLF11, is a novel p300-dependent regulator of Pdx-1 (MODY4) transcription in pancreatic islet beta cells." in: The Journal of biological chemistry, Vol. 284, Issue 52, pp. 36482-90, (2009) (PubMed).
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- Target
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- Alternative Name
- PDX1 (PDX1 Products)
- Background
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Description: The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Aliases: GSF, IPF1, IUF1, IDX-1, MODY4, PDX-1, STF-1
- Molecular Weight
- 30.8kDa
- Gene ID
- 3651
- HGNC
- 3651
- UniProt
- P52945
- Pathways
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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