VASP antibody

Catalog No. ABIN967240

Product Details anti-VASP Antibody

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VASP antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Specificity: VASP (Ab-238) antibody detects endogenous levels of total VASP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized non-phosphopeptide derived from human VASP around the phosphorylation site of serine 238 (K-V-SP-K-Q).

Application Details

Application Notes: WB: 1:500~1:1000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

References for anti-VASP antibody (ABIN967240)

Wang, Lu, Jin, Udo, Kandel, de Vente, Walter, Lohmann, Hawkins, Antonova: "Presynaptic and postsynaptic roles of NO, cGK, and RhoA in long-lasting potentiation and aggregation of synaptic proteins." in: Neuron, Vol. 45, Issue 3, pp. 389-403, (2005) (PubMed).

Jensen, Selheim, Døskeland, Gear, Holmsen: "Protein kinase A mediates inhibition of the thrombin-induced platelet shape change by nitric oxide." in: Blood, Vol. 104, Issue 9, pp. 2775-82, (2004) (PubMed).

Zhuang, Nguyen, Chen, Gudi, Eigenthaler, Jarchau, Walter, Boss, Pilz: "Vasodilator-stimulated phosphoprotein activation of serum-response element-dependent transcription occurs downstream of RhoA and is inhibited by cGMP-dependent protein kinase phosphorylation." in: The Journal of biological chemistry, Vol. 279, Issue 11, pp. 10397-407, (2004) (PubMed).

Smolenski, Bachmann, Reinhard, Hönig-Liedl, Jarchau, Hoschuetzky, Walter: "Analysis and regulation of vasodilator-stimulated phosphoprotein serine 239 phosphorylation in vitro and in intact cells using a phosphospecific monoclonal antibody." in: The Journal of biological chemistry, Vol. 273, Issue 32, pp. 20029-35, (1998) (PubMed).

Butt, Abel, Krieger, Palm, Hoppe, Hoppe, Walter: "cAMP- and cGMP-dependent protein kinase phosphorylation sites of the focal adhesion vasodilator-stimulated phosphoprotein (VASP) in vitro and in intact human platelets." in: The Journal of biological chemistry, Vol. 269, Issue 20, pp. 14509-17, (1994) (PubMed).

Target Details for VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Alternative Name: VASP (VASP Products)

Pathways: TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation