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p53 antibody

TP53 Reactivity: Human IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN966758
  • Target See all p53 (TP53) Antibodies
    p53 (TP53) (Tumor Protein P53 (TP53))
    Reactivity
    • 824
    • 252
    • 208
    • 104
    • 47
    • 33
    • 31
    • 18
    • 10
    • 9
    • 7
    • 6
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 623
    • 218
    • 6
    • 2
    • 1
    Rabbit
    Clonality
    • 559
    • 290
    • 1
    Polyclonal
    Conjugate
    • 477
    • 38
    • 31
    • 19
    • 18
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 13
    • 12
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This p53 antibody is un-conjugated
    Application
    • 662
    • 298
    • 247
    • 200
    • 199
    • 148
    • 124
    • 122
    • 119
    • 64
    • 59
    • 32
    • 18
    • 16
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC)
    Specificity
    P53 (Ab-15) antibody detects endogenous levels of total p53 protein.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    The antiserum was produced against synthesized non-phosphopeptide derived from human p53 around the phosphorylation site of serine15 (P-L-SP-Q-E).
    Top Product
    Discover our top product TP53 Primary Antibody
  • Application Notes
    WB: 1:500~1:1000
    IHC: 1:50~1:100.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100ug/100ul.
    Buffer
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Lin, Chao, Saito, Mazur, Murphy, Appella, Xu: "p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression." in: Nature cell biology, Vol. 7, Issue 2, pp. 165-71, (2005) (PubMed).

    Vega, Sevilla, Lazo: "p53 Stabilization and accumulation induced by human vaccinia-related kinase 1." in: Molecular and cellular biology, Vol. 24, Issue 23, pp. 10366-80, (2004) (PubMed).

    Li, Zhang, Sejas, Bagby, Pang: "Hypoxia-induced nucleophosmin protects cell death through inhibition of p53." in: The Journal of biological chemistry, Vol. 279, Issue 40, pp. 41275-9, (2004) (PubMed).

  • Target
    p53 (TP53) (Tumor Protein P53 (TP53))
    Alternative Name
    P53 (TP53 Products)
    Pathways
    p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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