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Beclin 1 antibody

BECN1 Reactivity: Human WB, ELISA, IHC, FACS Host: Mouse Monoclonal 2A4 unconjugated
Catalog No. ABIN965657
  • Target See all Beclin 1 (BECN1) Antibodies
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    Reactivity
    • 168
    • 75
    • 60
    • 9
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 135
    • 36
    • 2
    Mouse
    Clonality
    • 134
    • 39
    Monoclonal
    Conjugate
    • 93
    • 13
    • 10
    • 9
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Beclin 1 antibody is un-conjugated
    Application
    • 135
    • 75
    • 48
    • 37
    • 32
    • 26
    • 23
    • 17
    • 17
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human BECN1 expressed in E. Coli.
    Clone
    2A4
    Isotype
    IgG1
    Top Product
    Discover our top product BECN1 Primary Antibody
  • Application Notes
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Flow cytometry: 1/200 - 1/400.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Pickford, Masliah, Britschgi, Lucin, Narasimhan, Jaeger, Small, Spencer, Rockenstein, Levine, Wyss-Coray: "The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice." in: The Journal of clinical investigation, Vol. 118, Issue 6, pp. 2190-9, (2008) (PubMed).

  • Target
    Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
    Alternative Name
    BECN1 (BECN1 Products)
    Background
    Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 (PubMed 19270693)).(supplied by OMIM).
    Tissue specificity: Ubiquitous.
    Synonyms: ATG6, VPS30, beclin1, BECN1
    Molecular Weight
    60kDa
    Gene ID
    8678
    Pathways
    Autophagy
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