CD6 antibody

Catalog No. ABIN962073

Product Details anti-CD6 Antibody

Target: CD6

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD6 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Recognizes human CD6, also known as T12 or TP120. CD6 is a ~100-130 kD type 1 single pass trans-membrane protein member of the immunoglobulin superfamily. CD6 possesses 3 scavenger receptor cysteine rich domains in it's extracellular sequence. The membrane proximal SRCR3 contains the epitope responsible for interaction with CD166, also known as Activated Leukocyte Cell Adhesion Molecule or CD166. Multiple gene transcripts have been detected encoding CD6 in man resulting in the production of a number of CD6 isoforms. Recognizes an external epitope located in the membrane-distal SRCR domain 1 and is expected to recognize all CD6 isoforms so far identified,. CD6 has been implicated as a therapeutic target for a number of autoimmune conditions including Sjogren's syndrome, rheumatoid arthritis and psoriasis.

Purification: Protein G purified

Immunogen: Purified CD6 antigen.

Type of Immunogen: Purified protein

Clone: MEM-98

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1), IHC, IHC-P (10 μg/mL), IP, WB

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for CD6

Target: CD6

Alternative Name: CD6 (CD6 Products)

Background: Name/Gene ID: CD6

Synonyms: CD6, CD6 Molecule, T12, TP120, CD6 antigen

Gene ID: 923

UniProt: P30203