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ITGB1 antibody

ITGB1 Reactivity: Human WB, FACS, IP, Func Host: Mouse Monoclonal BV7 unconjugated

Catalog No. ABIN960569

Datasheet as PDF

Target See all ITGB1 Antibodies

ITGB1 (Integrin beta 1 (ITGB1))
Reactivity
209

94

77

21

18

18

17

10

8

8

7

3

2

2

2

2

2

2

1

1

1
Human
Host
150

71

14

6

4

1
Mouse
Compatible Secondaries
Clonality
139

103

1
Monoclonal
Conjugate
111

22

21

14

9

6

6

6

4

4

4

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
This ITGB1 antibody is un-conjugated
Application
119

116

71

56

34

27

27

26

26

19

13

7

5

4

3

3

3

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)

Specificity

This monoclonal antibody (subclass IgG1) binds to human b1-integrin chain present on tumor cells. BV7 is active on HT-29 colon carcinoma cells and on HCCP-2998 tumor cells. BV7 binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does not affect adhesion to endothelial cells.

Purification

Purified

Immunogen

Type of Immunogen: Native protein

Clone

BV7

Isotype

IgG1

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anti-Integrin beta 1 (ITGB1) (AA 25-100) antibody
ITGB1 Reactivity: Human, Mouse, Rat, Sheep, Rabbit WB, FACS, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 1 (ITGB1) antibody
ITGB1 Reactivity: Human WB, FACS, ELISA, IHC Host: Mouse Monoclonal 3B6 unconjugated

anti-Integrin beta 1 (ITGB1) (AA 140-383) antibody
ITGB1 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 1 (ITGB1) antibody
ITGB1 Reactivity: Human, Pig, Dog WB, FACS, IP Host: Mouse Monoclonal MEM-101A unconjugated

anti-Integrin beta 1 (ITGB1) antibody (PE)
ITGB1 Reactivity: Human, Pig, Dog FACS Host: Mouse Monoclonal MEM-101A PE

anti-Integrin beta 1 (ITGB1) (AA 297-380) antibody
ITGB1 Reactivity: Human WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 1 (ITGB1) antibody
ITGB1 Reactivity: Human WB, FACS, ELISA, IHC, IF Host: Rabbit Monoclonal 32A10 unconjugated Recombinant Antibody

anti-Integrin beta 1 (ITGB1) (AA 454-714) antibody
ITGB1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Integrin beta 1 (ITGB1) (AA 140-383) antibody
ITGB1 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C2 unconjugated

anti-Integrin beta 1 (ITGB1) antibody (FITC)
ITGB1 Reactivity: Human, Pig, Dog FACS Host: Mouse Monoclonal MEM-101A FITC

Application Notes

Approved: Flo, Func, IP, WB

Usage: For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. For neutralization of biological activity in vitro dilutions have to be made according to the amounts of beta1 integrin to be inactivated.

Comment

Target Species of Antibody: Human

Restrictions

For Research Use only
Format

Liquid

Concentration

Lot specific

Buffer

PBS, 0.1 % BSA

Storage

4 °C

Storage Comment

4°C. Store undiluted.
Target

ITGB1 (Integrin beta 1 (ITGB1))

Alternative Name

ITGB1 / Integrin Beta 1 / CD29 (ITGB1 Products)

Background

Name/Gene ID: ITGB1
Family: Integrin

Synonyms: ITGB1, CD29, CD29 antigen, Integrin beta-1, MDF2, MSK12, Integrin VLA-4 beta subunit, VLA-BETA, VLAB, Beta 1 integrin, FNRB, GPIIA, Integrin Beta 1, VLA-4 subunit beta

Gene ID

3688

UniProt

P05556

Pathways

Cell-Cell Junction Organization, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex, SARS-CoV-2 Protein Interactome