CD94 antibody (FITC)

Catalog No. ABIN951437

Product Details anti-CD94 Antibody (FITC)

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD94 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: Anti-mouse CD94 monoclonal antibody detects the mouse CD94 receptor.

Immunogen: Murine T cell clone AE7 cells Donor: Lewis Rat spleen cells Fusion Partner: Murine myeloma cell line SP2/0

Clone: 15F-18D1

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,1 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD94

Target: CD94 (KLRD1) (Killer Cell Lectin-Like Receptor Subfamily D, Member 1 (KLRD1))

Alternative Name: CD94 (KLRD1 Products)

Background: CD94 is a 180 amino acid, 70 KDa transmembrane glycoprotein that belongs to a family of murine Natural Killer (NK) cell receptors for MHC class I and is co-expressed as a heterodimer with NKG2 on the cellular surface. CD94 is expressed on NK cells as well as NK T cells. Both the murine CD94/NKG2 heterodimer and its human homologue are expressed on Th1 but not Th2 cells. Similar in function to the NKG2 family of receptors, CD94 is involved in NK target cell recognition, functions as an inhibitory receptor and plays an important role in adhesion and activation of the NK cell lineage. The unique expression of the CD94/NKG2 heterodimer on the Th1 subset of activated CD4+ cells suggests the potential use of our CL8950AP antibody in cell differentiation studies.Synonyms: KLRD1, KP43, Killer cell lectin-like receptor subfamily D member 1, NK cell receptor, Natural killer cells antigen CD94

Gene ID: 16643

NCBI Accession: NP_034784

UniProt: O54707