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- Target See all CD80 Antibodies
- CD80
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD80 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- This antibody recognises the murine CD80 cell surface protein, also known as B7-1.
- Cross-Reactivity (Details)
- Species reactivity (tested):Mouse.
- Purification
- Purified
- Clone
- RMMP-1
- Isotype
- IgG2a
- Top Product
- Discover our top product CD80 Primary Antibody
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reactivity: Human FACS, ELISA, IHC Host: Mouse Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reactivity: Mouse, Dog FACS, IP, IHC (fro) Host: Armenian Hamster Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reactivity: Mouse WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 FITC
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PerCP
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 APC
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PE
anti-CD80 (CD80) antibodyCD80 Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 2A2 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative and EIA grade BSA to bring total protein concentration to 4-5 mg/mL
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- DO NOT FREEZE! This product is photosensitive and should be protected from light.
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Target
- CD80
- Alternative Name
- CD80 (CD80 Products)
- Background
- CD80 is a member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages, and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
- Gene ID
- 12519
- NCBI Accession
- NP_033985
- UniProt
- Q00609
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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