CD55 antibody

Catalog No. ABIN951354

Product Details anti-CD55 Antibody

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This DAF Monoclonal Antibody (Clone: RIKO-3) detects Mouse DAF

Purification: Protein G Affinity Chromatography.

Immunogen: GPI-DAF transfected CHO cells from Armenian Hamster spleen. Fusion Partner: P3U1

Clone: RIKO-3

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55 / DAF (CD55 Products)

Background: DAF is one of several membrane proteins that prevent host cells from homologous complement attack. The two mouse DAF isoforms are effective against rat complement, but not against human and guinea pig complement. GPI-DAF is expressed on erythrocytes, spleen and testis while TM-DAF (transmembrane-DAF) is expressed only in testis. Both types of DAF transfectants avoided C3 deposition more successfully than non-transfectant cells.Synonyms: Complement decay-accelerating factor

Gene ID: 13136

NCBI Accession: NP_034146

UniProt: Q61475

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity