alpha-Mannosidase II antibody (Middle Region)

Catalog No. ABIN950381

Product Details anti-alpha-Mannosidase II Antibody

Target: alpha-Mannosidase II (MAN2A1) (Mannosidase, Alpha, Class 2A, Member 1 (MAN2A1))

Binding Specificity: AA 456-482, Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This alpha-Mannosidase II antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody recognizes Human Alpha-Mannosidase-2 / MAN2A1 (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 456-482 amino acids from the Central region of human Alpha-Mannosidase 2 / MAN2A1

Isotype: Ig Fraction

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for alpha-Mannosidase II

Target: alpha-Mannosidase II (MAN2A1) (Mannosidase, Alpha, Class 2A, Member 1 (MAN2A1))

Alternative Name: alpha-Mannosidase 2 / MAN2A1 (MAN2A1 Products)

Background: This gene encodes a protein which is a member of family 38 of the glycosyl hydrolases. The protein is located in the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.Synonyms: 3-1, 6-alpha-mannosidase, Alpha-mannosidase II, Golgi alpha-mannosidase II, MANA2, Mannosidase 2, Mannosidase alpha class 2A member 1, Mannosyl-oligosaccharide 1

Molecular Weight: 131141 Da

Gene ID: 4124

NCBI Accession: NP_002363