CD3 antibody
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- Target See all CD3 Antibodies
- CD3
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD3 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Western Blotting (WB), ELISA
- Sterility
- 0.2 μm filtered
- Immunogen
- CD3 antibody was raised in Mouse using a purified recombinant fragment of human CD3 expressed in E. coli as the immunogen.
- Clone
- 4D10A6
- Isotype
- IgG2a
- Top Product
- Discover our top product CD3 Primary Antibody
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- Application Notes
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ELISA: 1:10,000, FC: 1:200-1:400, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. - Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Supplied lyophilized from a 0.2 µm filtered solution in PBS.
- Handling Advice
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. - Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- Target
- CD3
- Alternative Name
- CD3 (CD3 Products)
- Background
- In immunology, the CD3 T-Cell Co-Receptor is a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3 Delta chain and two CD3 Epsilon chains. These chains associate with a molecule known as the T cell receptor (TCR) and the Zeta-chain to generate an activation signal in T lymphocytes. The TCR, Zeta-chain and CD3 molecules together comprise the TCR complex. Synonyms: Monoclonal CD3 antibody, Anti-CD3 antibody, Cluster of differentiation 3 antibody.
- Pathways
- TCR Signaling, Ubiquitin Proteasome Pathway
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