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Smooth Muscle Actin antibody (N-Term)

ACTA2 Reactivity: Human, Rat, Mouse, Chicken, Cow, Rabbit, Monkey IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783900
  • Target See all Smooth Muscle Actin (ACTA2) Antibodies
    Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
    Binding Specificity
    • 45
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 122
    • 76
    • 75
    • 29
    • 25
    • 22
    • 21
    • 15
    • 15
    • 14
    • 14
    • 13
    • 13
    • 13
    • 9
    • 7
    • 2
    • 1
    Human, Rat, Mouse, Chicken, Cow, Rabbit, Monkey
    Host
    • 73
    • 49
    • 1
    Rabbit
    Clonality
    • 80
    • 43
    Polyclonal
    Conjugate
    • 60
    • 8
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Smooth Muscle Actin antibody is un-conjugated
    Application
    • 63
    • 52
    • 37
    • 36
    • 28
    • 22
    • 18
    • 14
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. It reacts with tumors arising from smooth muscles and myoepithelial cells. Actin from fibroblasts (beta- and gamma-cytoplasmic), striated muscle (alpha-sarcomeric), and myocardium (alpha-myocardial) are not labeled.
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Rabbit, Chicken, Bovine and Baboon.
    Species reactivity (tested):Human.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    A synthetic peptide from N-terminus of Human alpha smooth muscle isoform of Actin Genename: ACTA2
    Isotype
    IgG
    Top Product
    Discover our top product ACTA2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    10 mM PBS, pH 7.4, 0.09 % Sodium Azide, BSA
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Target
    Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
    Abstract
    ACTA2 Products
    Background
    Actin alpha 2, the human aortic smooth muscle actin gene, is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein
    Gene ID
    59
    NCBI Accession
    NP_001135417
    Pathways
    Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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