SOX2 antibody (AA 76-80)
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- Target See all SOX2 Antibodies
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Binding Specificity
- AA 76-80
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SOX2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- G-A-E-W-K
- Specificity
- This antibody detects endogenous level of total SOX2 protein.
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse
- Purification
- Affinity-chromatography using epitope-specific peptide
- Immunogen
- Peptide sequence around aa.76~80 derived from SOX2
- Top Product
- Discover our top product SOX2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store (in aliquots) at -20 °C.
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- Target
- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
- Alternative Name
- SOX2 (SOX2 Products)
- Background
- Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.Synonyms: ANOP3, MCOPS3, SRY (sex determining region Y)-box 2, SRY-box 2, SRY-related HMG-box gene 2, Transcription factor SOX-2
- Molecular Weight
- 35 kDa
- Gene ID
- 6657
- NCBI Accession
- NP_003097
- UniProt
- P48431
- Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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