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CD3 antibody

Name: CD3 antibody
SKU: ABIN781714
Price: 762 USD
Availability: InStock

CD3 Reactivity: Human, Rhesus Monkey FACS, IHC (fro) Host: Mouse Monoclonal CRIS-7 unconjugated

Immunohistochemistry (IHC) image for anti-CD3 (CD3) antibody (ABIN781714) (CD3 antibody)

IHC

1 image

Catalog No. ABIN781714

Datasheet as PDF

Target See all CD3 Antibodies

CD3
Reactivity
179

104

26

20

17

10

8

8

7

7

4

3

2

1
Human, Rhesus Monkey
Host
215

53

20

13

9

1
Mouse
Compatible Secondaries
Clonality
299

6

1
Monoclonal
Conjugate
92

39

32

23

23

11

9

8

6

5

5

5

4

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CD3 antibody is un-conjugated
Application
284

81

57

52

45

37

32

22

9

8

7

6

4

3

2

2

2

2

2

2

2

2

1

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity

This antibody detects Human CD3. Antigen Distribution on Isolated cells: Peripheral T cells.

Cross-Reactivity (Details)

Species reactivity (tested):Human, Rhesus Monkey.

Purification

Affinity Chromatography

Immunogen

Stimulated Human leukocytes

Clone

CRIS-7

Isotype

IgG2a

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CD3 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-57 Biotin

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CD3 Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal UCHT1 PerCP

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CD3 Reactivity: Human FACS Host: Mouse Monoclonal MEM-57 PerCP

anti-CD3 (CD3) antibody (APC)
CD3 Reactivity: Human FACS Host: Mouse Monoclonal MEM-57 APC

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Reconstitution

Restore by adding 0.5 mL distilled water

Buffer

Stock solution contains 0.2 mg/mL IgG, PBS, pH 7.2 with 5 mg/mL BSA as stabilizer and 0.09 % Sodium Azide as a preservative

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C/-20 °C

Storage Comment

Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD3

Alternative Name

CD3 (CD3 Products)

Background

The CD3 antigen is a protein complex composed of four distinct chains (CD3γ, CD3δ and two CD3ε) that associate with the T cell receptor (TCR) and the ζ-chain to generate an activation signal in T lymphocytes. The TCR, ζ-chain and CD3 Molecules together comprise the TCR complex. The CD3γ, CD3δ and CD3ε chains are highly related cell surface proteins of the immunoglobulin superfamily containing a single extracellular immunoglobulin domain.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

Gene ID

916

NCBI Accession

NP_000724

UniProt

P07766

Pathways

TCR Signaling, Ubiquitin Proteasome Pathway