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OxLDL antibody

OxLDL Reactivity: Mouse, Human IF (p), FACS, IF (cc), IHC (p), ELISA, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN733148
  • Target See all OxLDL Antibodies
    OxLDL (Oxidized Low Density Lipoprotein (OxLDL))
    Reactivity
    Mouse, Human
    Host
    • 16
    Rabbit
    Clonality
    • 16
    Polyclonal
    Conjugate
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OxLDL antibody is un-conjugated
    Application
    • 13
    • 12
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Mouse
    Purification
    Purified by Protein A.
    Immunogen
    Full length plasma protein (Human)
    Isotype
    IgG
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Wang, Li, Zhen, Xu, Sun: "Simvastatin ameliorates renal lipidosis through the suppression of renal CXCL16 expression in mice with adriamycin-induced nephropathy." in: International journal of clinical and experimental pathology, Vol. 8, Issue 12, pp. 15696-707, (2016) (PubMed).

    Martinez, Malireddi, Lu, Cunha, Pelletier, Gingras, Orchard, Guan, Tan, Peng, Kanneganti, Virgin, Green: "Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins." in: Nature cell biology, Vol. 17, Issue 7, pp. 893-906, (2015) (PubMed).

    Wen, Liu, Liu, Harris, Yao, Ding, Nie, Lu, Chen, An, Zang, Teng: "OxLDL-targeted iron oxide nanoparticles for in vivo MRI detection of perivascular carotid collar induced atherosclerotic lesions in ApoE-deficient mice." in: Journal of lipid research, Vol. 53, Issue 5, pp. 829-38, (2012) (PubMed).

  • Target
    OxLDL (Oxidized Low Density Lipoprotein (OxLDL))
    Alternative Name
    ox-LDL (OxLDL Products)
    Background

    Synonyms: ox-LDL: Cu2SO4 oxidized low density lipoprotein, oxidized low density lipoprotein, Low density lipoprotein, MDA oxidized LDL, MDA oxidized low density lipoprotein.

    Background: Low-density lipoprotein (LDL) is the carrier protein for cholesterol in the blood. LDL binds to its receptor on the capillary walls and thereby mediates the uptake and clearence of cholesterol from the circulation. In atherosclerotic lesions oxidatively modified LDL is found and oxidized LDL is specifically recognized and ingested by macrophages via scavenger receptor A and CD36. Oxidized LDL may be a marker of atherosclerosis but the precise changes in oxidized LDL are not well described. Low-density lipoprotein oxidised with Cu2SO4.

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