CD44 antibody (Exon v10) (PE-Cy7)

Catalog No. ABIN680606

Product Details anti-CD44 Antibody (PE-Cy7)

Target: CD44

Binding Specificity: Exon v10

Reactivity: Human, Mouse, Rat, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD44 antibody is conjugated to PE-Cy7

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificity: Excitation / Emission Wavelengths: 480,565,743nm/767nm

Purification: Antibodies are purified by protein A and peptide affinity chromatography.

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human CD44v10
Please inquire for sequence information.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1mg/1ml

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for CD44

Target: CD44

Alternative Name: CD44 (CD44 Products)

Synonyms: CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody

Background: CD44 is a receptor for hyaluronic acid (HA). It mediates cell-cell and cell-matrix interactions through its affinity for HA and possibly also through its affinity for other ligands such as osteopontin collagens and matrix matalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration tumor growth and progression. Also involved in lymphocyte activation recirculation and homing and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
Synonym: ECMR III, Epican, Heparan sulfate proteoglycan, HUTCH I, Hyaluronate receptor, PGP 1, CD44 antigen, CD44 molecule, CDw44, ECMR III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, Heparan sulfate proteoglycan, Hermes antigen, HUTCH I, Hyaluronate receptor, PGP 1, Phagocytic glycoprotein I.

Molecular Weight: 82kDa

Gene ID: 960

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling