Adiponectin Receptor 2 antibody (AA 315-340) (Cy7)

Catalog No. ABIN670857

Product Details anti-Adiponectin Receptor 2 Antibody (Cy7)

Target: Adiponectin Receptor 2 (ADIPOR2)

Binding Specificity: AA 315-340

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adiponectin Receptor 2 antibody is conjugated to Cy7

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificity: This antibody may cross react with Adiponectin receptor 1 due to sequence similarity.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Adiponectin receptor 2

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Adiponectin Receptor 2

Target: Adiponectin Receptor 2 (ADIPOR2)

Alternative Name: Adiponectin receptor 2 (ADIPOR2 Products)

Background:

Synonyms: PAQR2, ACDCR2, Adiponectin receptor protein 2, Progestin and adipoQ receptor family member II, ADIPOR2

Background: Receptor for globular and full-length adiponectin (APM1), an essential hormone secreted by adipocytes that acts as an antidiabetic. Probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. Mediates increased AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin. Has some intermediate-affinity receptor activity for both globular and full-length adiponectin.

Gene ID: 79602

UniProt: Q86V24

Pathways: AMPK Signaling