COL18A1 antibody (AA 1581-1680)

Catalog No. ABIN669951

Product Details anti-COL18A1 Antibody

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Binding Specificity: AA 1581-1680

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL18A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COL18A1/Endostatin

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-COL18A1 antibody (ABIN669951)

Imoto, Kumatani, Okada, Yamawaki: "Endostatin is protective against monocrotaline-induced right heart disease through the inhibition of T-type Ca(2+) channel." in: Pflügers Archiv : European journal of physiology, Vol. 468, Issue 7, pp. 1259-70, (2016) (PubMed).

Hu, Hu, Zhang, Jia, Qian, Yang, Li: "Clinical significance of serum and tumor tissue endostatin evaluation in operable non-small cell lung cancer." in: Biomedical reports, Vol. 2, Issue 6, pp. 898-904, (2014) (PubMed).

Gao, Zhao, Liang, Li, Cao, Liu: "Effect of peritoneal dialysis on expression of vascular endothelial growth factor, basic fibroblast growth factor and endostatin of the peritoneum in peritoneal dialysis patients." in: Nephrology (Carlton, Vic.), Vol. 16, Issue 8, pp. 736-42, (2011) (PubMed).

Target Details for COL18A1

Target: COL18A1 (Collagen, Type XVIII, alpha 1 (COL18A1))

Alternative Name: COL18A1 (COL18A1 Products)

Synonyms: KNO antibody, KNO1 antibody, KS antibody, cb371 antibody, cb529 antibody, fc96d06 antibody, sb:cb529 antibody, wu:fb47h10 antibody, wu:fb77g12 antibody, wu:fc50f04 antibody, wu:fc96d06 antibody, wu:fk02h12 antibody, kno antibody, kno1 antibody, collagen type XVIII alpha 1 chain antibody, collagen type XVIII alpha 1 chain a antibody, collagen, type XVIII, alpha 1 antibody, collagen type XVIII alpha 1 antibody, COL18A1 antibody, col18a1a antibody, Col18a1 antibody, col18a1 antibody

Background:

Synonyms: KS, KNO, KNO1, Collagen alpha-1(XVIII) chain, COL18A1

Background: COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.

Gene ID: 80781

UniProt: P39060