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Dynamitin antibody (AA 192-219)

DCTN2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB19599 unconjugated
Catalog No. ABIN656819
  • Target See all Dynamitin (DCTN2) Antibodies
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Binding Specificity
    • 15
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 192-219
    Reactivity
    • 41
    • 35
    • 17
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 49
    • 5
    • 3
    Rabbit
    Clonality
    • 54
    • 3
    Polyclonal
    Conjugate
    • 32
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dynamitin antibody is un-conjugated
    Application
    • 45
    • 17
    • 13
    • 13
    • 9
    • 9
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    B, M, Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This DCTN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human DCTN2.
    Clone
    RB19599
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DCTN2 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    DCTN2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    Expiry Date
    6 months
  • Target
    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))
    Alternative Name
    DCTN2 (DCTN2 Products)
    Background
    This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
    Molecular Weight
    44231
    Gene ID
    10540
    NCBI Accession
    NP_001248341, NP_001248342, NP_006391
    UniProt
    Q13561
    Pathways
    M Phase, Ribonucleoprotein Complex Subunit Organization
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