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OCT4 antibody (AA 265-297)
POU5F1
Reactivity: Human
WB, IHC (p)
Host: Rabbit
Polyclonal
RB14495
unconjugated
Product Details anti-OCT4 Antibody
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Target
See all OCT4 (POU5F1) Antibodies
OCT4 (POU5F1)
(POU Class 5 Homeobox 1 (POU5F1))
Binding Specificity
All epitopes for OCT4 antibodies
AA 265-297
Reactivity
All reactivities for OCT4 antibodies
Human
Host
All hosts for OCT4 antibodies
Rabbit
Clonality
All clonalities for OCT4 antibodies
Polyclonal
Conjugate
All conjugates for OCT4 antibodies
This OCT4 antibody is un-conjugated
Application
All applications for OCT4 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This OCT3/4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-297 amino acids from human OCT3/4.
Clone
RB14495
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000. IHC-P: 1:50~100
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for OCT4
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Target
OCT4 (POU5F1)
(POU Class 5 Homeobox 1 (POU5F1))
Alternative Name
OCT3/4 (POU5F1 Products )
Background
This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6,22)(p21,q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Molecular Weight
38571
Gene ID
5460
NCBI Accession
NP_002692
UniProt
Q01860
Pathways
Stem Cell Maintenance
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