IFT88 antibody (C-Term)

Catalog No. ABIN655090

Product Details anti-IFT88 Antibody

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Binding Specificity: AA 791-820, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT88 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This IFT88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 791-820 amino acids from the C-terminal region of human IFT88.

Clone: RB24875

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-IFT88 antibody (ABIN655090)

Xiang, Guo, Cheng, Zhang, Huang, Wang, Ma, Xu: "HDAC6 inhibition suppresses chondrosarcoma by restoring the expression of primary cilia." in: Oncology reports, Vol. 38, Issue 1, pp. 229-236, (2018) (PubMed).

Zhan, Xiang, Guo, Ma: "Basic fibroblast growth factor increases IFT88 expression in chondrocytes." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 6590-6599, (2018) (PubMed).

Xiang, Jiang, Guo, Gong, Yang, Wu, Huang, Cheng, Xu: "Hedgehog pathway inhibitor-4 suppresses malignant properties of chondrosarcoma cells by disturbing tumor ciliogenesis." in: Oncology reports, Vol. 32, Issue 4, pp. 1622-30, (2014) (PubMed).

Target Details for IFT88

Target: IFT88 (Intraflagellar Transport 88 Homolog (IFT88))

Alternative Name: IFT88 (IFT88 Products)

Background: This gene encodes a member of the tetratrico peptide repeat (TPR) family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq].

Gene ID: 8100

NCBI Accession: NP_006522, NP_783195

UniProt: Q13099

Pathways: Hedgehog Signaling, Sensory Perception of Sound