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AIF antibody (N-Term)

AIFM1 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB22966 unconjugated
Catalog No. ABIN652856
  • Target See all AIF (AIFM1) Antibodies
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Binding Specificity
    • 15
    • 9
    • 8
    • 7
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-98, N-Term
    Reactivity
    • 105
    • 58
    • 55
    • 22
    • 11
    • 11
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Human
    Host
    • 93
    • 9
    • 2
    • 2
    Rabbit
    Clonality
    • 90
    • 15
    Polyclonal
    Conjugate
    • 64
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIF antibody is un-conjugated
    Application
    • 81
    • 36
    • 32
    • 27
    • 21
    • 14
    • 13
    • 13
    • 12
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This AIFM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the N-terminal region of human AIFM1.
    Clone
    RB22966
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AIFM1 Primary Antibody
  • Application Notes
    IF: 1:200. IF: 1:200. WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    Alternative Name
    AIFM1 (AIFM1 Products)
    Background
    AIFM1 is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this protein induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9.
    Molecular Weight
    66901
    Gene ID
    9131
    NCBI Accession
    NP_001124318, NP_001124319, NP_004199, NP_665811, NP_665812
    UniProt
    O95831
    Pathways
    Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
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