CD22 antibody
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- Target See all CD22 Antibodies
- CD22 (CD22 Molecule (CD22))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD22 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Specificity
- B-ly8, produces mouse IgG1 immunoglobulins directed against human CD22, molecular weight 130-140 kD
- Purity
- PURE
- Clone
- B-ly8
- Isotype
- IgG1
- Top Product
- Discover our top product CD22 Primary Antibody
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- Application Notes
- immunohistochemistry on cytospots, immunohistochemistry on frozen tissue sections
- Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- 4 °C
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- Target
- CD22 (CD22 Molecule (CD22))
- Alternative Name
- CD22 (CD22 Products)
- Background
- Antigen distribution: CD22 is detected in the cytoplasm early in B cell development (late pro-B cell stage), appears on the cell surface simultaneously with surface IgD, and is found on most mature B cells. Expression is lost with terminal differentiation of B cells and is absent on plasma cells. Activation of B cells via surface Ig increases CD22 expression [1]. CD22 reacts with most B cell leukemias including Hairy Cell Leukemia (HCL) and B cell lymphomas. Cellular Expression: Pan B cells, (surface and cytoplasmatic staining).
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