Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

CD16 antibody

CD16 Reactivity: Human FACS, ICC Host: Mouse Monoclonal B-E16 unconjugated
Catalog No. ABIN6253847
  • Target See all CD16 Antibodies
    CD16
    Reactivity
    • 128
    • 26
    • 20
    • 20
    • 20
    • 9
    • 8
    • 8
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Human
    Host
    • 109
    • 25
    • 19
    • 1
    Mouse
    Clonality
    • 129
    • 23
    • 1
    Monoclonal
    Conjugate
    • 59
    • 18
    • 14
    • 13
    • 7
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD16 antibody is un-conjugated
    Application
    • 126
    • 34
    • 26
    • 26
    • 25
    • 24
    • 21
    • 15
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Specificity
    B-E16 produces mouse IgG2a immunoglobulins specific for a 50-70 kD antigen which is associated with the IgG FceRI on NK cells, neutrophils, granulocytes and monocytes [3]
    Purity
    PURE
    Clone
    B-E16
    Isotype
    IgG2a
    Top Product
    Discover our top product CD16 Primary Antibody
  • Application Notes
    immunohistochemistry on cytospots,  immunohistochemistry on frozen tissue
    Restrictions
    For Research Use only
  • Format
    Liquid
    Storage
    4 °C
  • Target
    CD16
    Alternative Name
    CD16 (CD16 Products)
    Background
    Antigen distribution: CD16 is a low-affinity receptor for aggregated IgG (FcgRIII) [1,2]. The transmembrane form of CD16 is expressed on approximately 15% of peripheral blood lymphocytes and is present on virtually all resting NK cells. It is also found on macrophages and mast cells. It binds IgG complexed to antigens and mediates phagocytosis and antibody-dependent cellular cytotoxicity. On NK cells it mediates signal transduction while the GPI-linked form on neutrophils binds to ligands but is unable to induce any signal or functional effect [1]. Cellular Expression: NK cells, neutrophils, granulocytes, macrophages.
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
You are here:
Support