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Vimentin antibody (Biotin)

VIM Reactivity: Human IHC Host: Mouse Monoclonal Biotin

Catalog No. ABIN645827

Datasheet as PDF

Target See all Vimentin (VIM) Antibodies

Vimentin (VIM)
Reactivity
304

120

117

60

60

49

42

37

29

21

20

13

13

8

8

6

6

3

3

2

1

1

1

1

1

1

1

1

1
Human
Host
158

129

11

6

6

5

2
Mouse
Compatible Secondaries
Clonality
172

144
Monoclonal
Conjugate
198

14

13

12

9

7

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1
This Vimentin antibody is conjugated to Biotin
Application
263

115

103

97

88

64

48

40

39

33

23

20

8

5

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1
Immunohistochemistry (IHC)

Purpose

Mouse Anti-Human Vimentin, Biotinylated

Cross-Reactivity (Details)

Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

Characteristics

Collagen & Extracellular Matrix Proteins

Immunogen

Purified Human Vimentin.

Isotype

IgG1

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VIM Reactivity: Mammalian WB, FACS, IHC (p), ICC Host: Mouse Monoclonal VI-01 unconjugated

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VIM Reactivity: Human, Mouse, Rat, Pig, Chicken WB, IHC (p), ICC, IP Host: Mouse Monoclonal VI-10 unconjugated

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VIM Reactivity: Human, Mouse WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB41034 unconjugated

anti-Vimentin (VIM) (AA 1-200) antibody
VIM Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

anti-Vimentin (VIM) antibody
VIM Reactivity: Human WB, IHC, ICC, IP Host: Mouse Monoclonal C8 unconjugated

anti-Vimentin (VIM) (AA 430-457), (C-Term) antibody
VIM Reactivity: Human WB, IF, FACS, IHC (p) Host: Rabbit Polyclonal RB16691 unconjugated

anti-Vimentin (VIM) (AA 2-466) antibody
VIM Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 3A1F2 unconjugated

anti-Vimentin (VIM) antibody
VIM Reactivity: Human, Pig, Cow, Chicken, Dog, Cat, Goat WB, IHC, FACS, StM Host: Mouse Monoclonal VM452 unconjugated

Application Notes

Immunohistochemistry.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

Restrictions

For Research Use only
Format

Lyophilized

Reconstitution

Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Concentration

1 mg/ml in PBS (after reconstitution).

Storage

-20 °C

Storage Comment

-20°C
Target

Vimentin (VIM)

Alternative Name

Vimentin (VIM Products)

Background

Target Description: Vimentin expression in human malignant glioma cells depends on cellular density, algorithms of drug delivery and chemo/radio treatment. Vimentin and detyrosinated microtubules provide structural support for the extensive microtentacles observed in detached tumor cells and a mechanism to promote successful metastatic spread. Primary colorectal carcinomas display aberrant expression of vimentin, and have activated Notch and TGFbeta signaling pathways. Vimentin is a strong arterial substrate for transglutaminases. Transglutaminase-mediated vimentin dimerization results in a novel unifying pathway by which vasodilatory and remodeling responses may be regulated. Ablation of vimentin expression inhibits migration and invasion of colon and breast cancer cell lines.< div class='ty-product-feature'>< div class='ty-product-feature__label'>Cross Reactivity< div class='ty-product-feature__value'>Vimentin antibody will recognize most mammalian Vimentin except mouse and rat.

Pathways

Caspase Cascade in Apoptosis