CD44 antibody (FITC)

Catalog No. ABIN645543

Product Details anti-CD44 Antibody (FITC)

Target: CD44

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD44 antibody is conjugated to FITC

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Characteristics: Rat Anti-Mouse CD44, FITC-labeled

Immunogen: CD44 enriched mouse LN T cells.

Isotype: IgG

Application Details

Application Notes: Immunohistochemistry, Immunocytochemistry,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.Recommended

Concentration: 1 mg/ml in PBS (after reconstitution).

Storage: -20 °C

Storage Comment: Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Target Details for CD44

Target: CD44

Alternative Name: CD44 (CD44 Products)

Background: CD44 is a cell-surface glycoprotein that plays a role in cell-cell interactions, cell adhesion and migration. CD44 is a receptor for hyaluronic acid and also interacts with other ligands, such as osteopontin, collagens, and matrix metalloproteinases. CD44 participates in a wide variety of cellular functions such as lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. CD44 and CD49d are putative activity markers and CD44 a potential novel therapeutic target in multiple sclerosis. Increased CD44 antigen is associated with relapses in non-small cell lung cancers. Synonyms: MDU2, MDU3, MIC4, CDW44, CSPG8, HCELL, HUTCH-I, Phagocytic glycoprotein I, PGP-1, Extracellular matrix receptor-III, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican) CDw44.

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling