PD-1 antibody
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- Target See all PD-1 (PDCD1) Antibodies
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Reactivity
- Mouse
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Host
- Rat
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Conjugate
- This PD-1 antibody is un-conjugated
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Application
- Flow Cytometry (FACS)
- Specificity
- DS-MB-03795 recognizes mouse CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. DS-MB-03795 does not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.
- Characteristics
- Rat Anti-Mouse CD279
- Purification
- Purified
- Immunogen
- PD-1 transferred BHK cells
- Isotype
- IgG2b
- Top Product
- Discover our top product PDCD1 Primary Antibody
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- Restrictions
- For Research Use only
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- Concentration
- IgG concentration 1.0 mg/ml
- Buffer
- Phosphate buffered saline, pH7.4
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Alternative Name
- CD279 (PDCD1 Products)
- Background
- Synonyms: PD1
- Pathways
- Cancer Immune Checkpoints
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