Macrophage Scavenger Receptor 1 antibody (Biotin)

Catalog No. ABIN642250

Product Details anti-Macrophage Scavenger Receptor 1 Antibody (Biotin)

Target: Macrophage Scavenger Receptor 1 (MSR1)

Reactivity: Mouse

Host: Rat

Conjugate: This Macrophage Scavenger Receptor 1 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Specificity: DS-MB-03764 recognizes the murine scavenger receptor class A (SRA), type I and II, also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions. DS-MB-03764 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion (1). Recent research shows that DS-MB-03764 recognizes an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice. DS-MB-03764 is therefore unsuitable for use with the C57BL/6 mouse strain (7).

Characteristics: Rat Anti-Mouse CD204, Biotinylated

Immunogen: RAW264 cell line

Isotype: IgG2b

Application Details

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 0.1 mg/ml

Buffer: Phosphate buffered saline pH7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Macrophage Scavenger Receptor 1

Target: Macrophage Scavenger Receptor 1 (MSR1)

Alternative Name: CD204 (MSR1 Products)